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Structural basis of augmenting taurine uptake by the taurine transporter in alleviating cellular senescence.

作者信息

Zhang Heng, Cui Nana, Ma Xiong, Xu H Eric

机构信息

The State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, State Key Laboratory for Oncogenes and Related Genes, NHC Key Laboratory of Digestive Diseases, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Institute of Digestive Disease, Shanghai, China.

出版信息

Cell Res. 2025 May;35(5):385-388. doi: 10.1038/s41422-025-01090-y. Epub 2025 Mar 20.

DOI:10.1038/s41422-025-01090-y
PMID:40108449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12012219/
Abstract
摘要

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Nature. 2024 Jun;630(8015):247-254. doi: 10.1038/s41586-024-07437-6. Epub 2024 May 15.
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Nat Struct Mol Biol. 2023 Jul;30(7):1012-1022. doi: 10.1038/s41594-023-00983-z. Epub 2023 Jul 3.
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Cryo-EM structure of GABA transporter 1 reveals substrate recognition and transport mechanism.GABA 转运蛋白 1 的冷冻电镜结构揭示了底物识别和转运机制。
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