Baier W K
Neuropediatrics. 1985 May;16(2):84-91. doi: 10.1055/s-2008-1052549.
Eighty-one patients suffering from childhood onset migraine and their families were investigated for familial prevalences of epileptic seizures and migraine. The incidence of epileptic seizures was not increased above the epidemiological risk. - In all, migraine is largely inherited from maternal ascendents, irrespective of the sex of the index case. Clinical subtypes of migraine ("non-focal migraine" and migraine accompagnée) are not accompanied by respectively increased familial prevalences. - Onset of migraine is earlier in patients with a higher familial impact. These findings are discussed in context with a proposed multifactorial pathogenesis of migraine.
对81名儿童期起病的偏头痛患者及其家属进行了癫痫发作和偏头痛家族患病率调查。癫痫发作的发生率并未高于流行病学风险。总体而言，偏头痛很大程度上是从母系遗传而来，与索引病例的性别无关。偏头痛的临床亚型（“非局灶性偏头痛”和偏头痛伴发症）并未分别伴有家族患病率的增加。家族影响较高的患者偏头痛发病更早。结合偏头痛的多因素发病机制对这些发现进行了讨论。
