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当前肺栓塞管理与结局的差异:美国心脏协会的科学声明

Disparities in Current Pulmonary Embolism Management and Outcomes: A Scientific Statement From the American Heart Association.

作者信息

Takahashi Edwin A, Sista Akhilesh K, Addison Daniel, Bikdeli Behnood, Bishay Vivian L, Gu Sue, Hood Maureen N, Litmanovich Diana, Misra Sanjay, Reddy Gautham

出版信息

Circulation. 2025 Apr 15;151(15):e944-e955. doi: 10.1161/CIR.0000000000001306. Epub 2025 Mar 20.

Abstract

Pulmonary embolism is a common cause of cardiovascular-associated morbidity and mortality. Although pulmonary embolism affects individuals from all demographics, the incidence of pulmonary embolism is higher among people from certain racial groups, reproductive-age women compared with age-matched men, and transgender people taking estrogen hormones. Furthermore, disparities may exist in the diagnosis or management strategies of pulmonary embolism associated with race, ethnicity, sex, or socioeconomic status, which may correlate with poorer downstream outcomes, including recurrent pulmonary embolism, chronic thromboembolic pulmonary hypertension, or short- or long-term mortality. This scientific statement summarizes disparities in diagnosis, treatment strategies, and outcomes related to pulmonary embolism, and reviews approaches to create equitable pulmonary embolism care and address the knowledge gaps in the literature.

摘要

肺栓塞是心血管相关发病和死亡的常见原因。尽管肺栓塞影响所有人口统计学群体的个体,但在某些种族群体、与年龄匹配的男性相比的育龄妇女以及服用雌激素的跨性别者中,肺栓塞的发病率更高。此外,在与种族、民族、性别或社会经济地位相关的肺栓塞诊断或管理策略方面可能存在差异,这可能与较差的下游结局相关,包括复发性肺栓塞、慢性血栓栓塞性肺动脉高压或短期或长期死亡率。本科学声明总结了与肺栓塞相关的诊断、治疗策略和结局方面的差异,并回顾了创建公平的肺栓塞护理以及解决文献中知识空白的方法。

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