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先天性偏瘫中的镜像运动不对称:对抑制假说的重新审视。

Mirror movement asymmetries in congenital hemiparesis: the inhibition hypothesis revisited.

作者信息

Nass R

出版信息

Neurology. 1985 Jul;35(7):1059-62. doi: 10.1212/wnl.35.7.1059.

DOI:10.1212/wnl.35.7.1059
PMID:4010948
Abstract

Mirror movements are seen in normal children in the first decade. The movements persist after age 10 in patients with congenital hemiparesis. At first, mirror movements are more prominent in the good hand (when the impaired hand attempts a unimanual task), but after age 10, mirroring diminishes in the good hand, and these movements are equally prominent in good and impaired hands. Maturational changes in callosally mediated inhibition of uncrossed motor pathways and reorganizational changes of the pyramidal motor system after early unilateral brain injury explain these age-dependent changes in asymmetries of mirror movements.

摘要

镜像运动在正常儿童的第一个十年中可见。在先天性偏瘫患者中,这些运动在10岁以后仍会持续存在。起初,镜像运动在优势手(当患侧手尝试单手任务时)更为明显,但在10岁以后,优势手的镜像运动减弱,且这些运动在优势手和患侧手中同样明显。胼胝体介导的对未交叉运动通路的抑制的成熟变化以及早期单侧脑损伤后锥体运动系统的重组变化解释了镜像运动不对称性的这些年龄依赖性变化。

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