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一名12岁儿童急性缺血性卒中揭示颈内动脉夹层:病例报告及文献综述

Acute ischemic stroke revealing an internal carotid artery dissection in a 12-year-old child: case report and literature review.

作者信息

Chahboun Bouchra, Mekkaoui Ikram, Kaba Ousmane, Zoubaa Yassmine, Laaribi Ilias, Bkiyar Houssam, Housni Brahim

机构信息

Intensive Care Unit, Mohammed VI University Hospital, Oujda, Morocco.

Faculty of Medicine and Pharmacy of Oujda, Mohamed First University, Oujda, Morocco.

出版信息

Ann Med Surg (Lond). 2025 Jan 9;87(1):372-375. doi: 10.1097/MS9.0000000000002818. eCollection 2025 Jan.

Abstract

INTRODUCTION AND IMPORTANCE

Internal carotid artery (ICA) dissection is a known cause of stroke but is often underdiagnosed in pediatric patients. Pediatric ischemic stroke significantly contributes to juvenile brain injury. Currently, there are no universally accepted guidelines for managing stroke in children.

CASE PRESENTATION

We report the case of a 12-year-old girl who was admitted with sudden left hemiplegia and aphasia. Imaging revealed right carotid artery dissection and ischemic stroke in the right middle cerebral artery territory. She was managed with aspirin (75 mg/day) and enoxaparin (3000 IU/12 h) and remains under observation with persistent symptoms.

CLINICAL DISCUSSION

This case highlights the difficulty in diagnosing ICA dissections in pediatric patients and the lack of clear guidelines for their management. The use of aspirin and enoxaparin represents an empirically-based therapeutic approach, underscoring the urgent need for further research to better understand the risk factors and pathogenic mechanisms of this condition. The persistence of symptoms in our patient also emphasizes the importance of close monitoring and individualized management.

CONCLUSION

ICA dissection in pediatric stroke is hard to diagnose and treat. Research, empirically-based treatments, and personalized monitoring are crucial for better management and outcomes.

摘要

引言与重要性

颈内动脉(ICA)夹层是已知的中风病因,但在儿科患者中常常诊断不足。小儿缺血性中风是导致青少年脑损伤的重要因素。目前,对于儿童中风的治疗尚无普遍接受的指南。

病例介绍

我们报告了一名12岁女孩的病例,她因突发左侧偏瘫和失语入院。影像学检查显示右侧颈动脉夹层和右侧大脑中动脉区域的缺血性中风。她接受了阿司匹林(75毫克/天)和依诺肝素(3000国际单位/12小时)治疗,目前仍在观察中,症状持续存在。

临床讨论

该病例凸显了儿科患者颈内动脉夹层诊断的困难以及缺乏明确的治疗指南。使用阿司匹林和依诺肝素是基于经验的治疗方法,这凸显了迫切需要进一步研究以更好地了解该病症的危险因素和发病机制。我们患者症状的持续也强调了密切监测和个体化治疗的重要性。

结论

小儿中风中的颈内动脉夹层难以诊断和治疗。研究、基于经验的治疗以及个性化监测对于更好的管理和治疗结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5d5/11918732/be9d34a84154/ms9-87-372-g001.jpg

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