O'Connell B K, Towfighi J, Brennan R W, Tyler W, Mathews M, Weidner W A, Saul R F
Neurology. 1985 Jul;35(7):993-7. doi: 10.1212/wnl.35.7.993.
We analyzed four personal cases and 51 reported cases of dissecting aneurysms of the arteries of the head and neck. Subintimal dissection more commonly affects the intracranial vessels before age 40. In contrast, medial dissection tends to affect extracranial vessels after age 30. Vertebrobasilar dissection more variably affects either arterial plane. The reasons for these differing patterns of dissection are still not clear. In young subjects, the subintimal layer appears to be more susceptible; in contrast, the media becomes increasingly vulnerable with age, particularly in the presence of acquired medial disease.
我们分析了4例个人病例以及51例已报道的头颈部动脉夹层动脉瘤病例。内膜下夹层在40岁之前更常累及颅内血管。相比之下，中膜夹层在30岁之后倾向于累及颅外血管。椎基底动脉夹层对任一动脉层面的影响更具多样性。这些不同夹层模式的原因仍不清楚。在年轻受试者中，内膜下层似乎更易受累；相比之下，中膜随着年龄增长变得越来越脆弱，尤其是在存在后天性中膜疾病的情况下。
