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Depression and anxiety, peripheral blood inflammatory factors, and stress levels on therapeutic outcomes in patients with chronic wounds.抑郁与焦虑、外周血炎症因子及应激水平对慢性伤口患者治疗结局的影响
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Research status of hormone replacement therapy on mood and sleep quality in menopausal women.激素替代疗法对绝经后女性情绪和睡眠质量的研究现状
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Peripheral Monocyte Percentage as a Potential Indicator of Prognosis in Patients with Chronic Subdural Hematoma Receiving Conservative Therapy.外周血单核细胞百分比作为慢性硬脑膜下血肿患者接受保守治疗的潜在预后指标。
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Perceived social support is strongly associated with recovery after injury.感知到的社会支持与受伤后的康复密切相关。
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A Narrative Review of Movement-Based Mind-Body Interventions: Effects of Yoga, Tai Chi, and Qigong for Back Pain Patients.基于运动的身心干预的叙述性综述:瑜伽、太极拳和气功对背痛患者的影响
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Deregulation of inflammatory response in the diabetic condition is associated with increased ischemic brain injury.糖尿病状态下炎症反应的失调与缺血性脑损伤增加有关。
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Anxiety, stress, depression, and patients' responses to periodontal treatment: periodontists' knowledge and professional behavior.焦虑、压力、抑郁与患者对牙周治疗的反应:牙周病医生的认知与专业行为
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抑郁、焦虑、炎症因子及应激水平对慢性创伤患者治疗效果的影响

Impact of depression, anxiety, inflammatory factors, and stress levels on treatment outcomes in patients with chronic trauma.

作者信息

Zhao Wei, Chen Wei-Guan, Zhang Long-Yao, Cui Zhi-Ming, Wang Xue-Jian

机构信息

Department of Neurosurgery, Affiliated Hospital 2 of Nantong University, Nantong 226000, Jiangsu Province, China.

Department of Rehabilitation Medicine, Affiliated Hospital 2 of Nantong University, Nantong 226000, Jiangsu Province, China.

出版信息

World J Psychiatry. 2025 Mar 19;15(3):103250. doi: 10.5498/wjp.v15.i3.103250.

DOI:10.5498/wjp.v15.i3.103250
PMID:40110001
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11886338/
Abstract

This editorial discusses a recent article published by Li in 2024, which highlights a critical yet underexplored dimension of chronic wound care: The impact of psychological factors such as depression and anxiety on treatment outcomes. With the increasing prevalence of chronic wounds in China, driven by population aging, traffic accidents, and chronic diseases, chronic wounds have emerged as a significant public health concern. They not only pose serious threats to individual health but also impose considerable social and economic burdens on healthcare systems. Against this backdrop, the study by Li aimed to explore how psychological distress affects the management and recovery of patients with chronic wounds. In their research, chronic wound patients were meticulously evaluated for depression and anxiety using validated psychological assessment scales and blood biomarkers. The findings reveal a stark reality: Individuals with severe depression and anxiety exhibit markedly lower treatment adherence, slower recovery rates, and diminished post-treatment quality of life. These psychological challenges hinder patients' active engagement with their care plans and may directly impede physiological healing processes. Importantly, the study underscored that factors such as wound size, anxiety, and depression significantly influence therapeutic outcomes in chronic wound patients. This insight calls for a more holistic approach to wound care, where addressing psychological well-being becomes an integral component of treatment protocols. As such, the study highlighted the necessity of early identification and targeted intervention for depression and anxiety in chronic wound patients. By prioritizing psychological support alongside medical treatment, healthcare providers can enhance therapeutic efficacy and improve patients' long-term quality of life. This integrative approach can not only optimize clinical outcomes but also alleviate the broader societal and economic impact of chronic wounds.

摘要

这篇社论讨论了李在2024年发表的一篇文章,该文章强调了慢性伤口护理中一个关键但尚未充分探索的方面:抑郁和焦虑等心理因素对治疗结果的影响。在中国,由于人口老龄化、交通事故和慢性病的推动,慢性伤口的患病率不断上升,慢性伤口已成为一个重大的公共卫生问题。它们不仅对个人健康构成严重威胁,还给医疗系统带来了相当大的社会和经济负担。在此背景下,李的研究旨在探讨心理困扰如何影响慢性伤口患者的治疗和康复。在他们的研究中,使用经过验证的心理评估量表和血液生物标志物对慢性伤口患者的抑郁和焦虑进行了细致评估。研究结果揭示了一个严峻的现实:患有严重抑郁和焦虑的个体治疗依从性明显较低,康复速度较慢,治疗后的生活质量下降。这些心理挑战阻碍了患者积极参与护理计划,可能直接妨碍生理愈合过程。重要的是,该研究强调伤口大小、焦虑和抑郁等因素对慢性伤口患者的治疗结果有显著影响。这一见解呼吁采用更全面的伤口护理方法,将解决心理健康问题作为治疗方案的一个组成部分。因此,该研究强调了对慢性伤口患者的抑郁和焦虑进行早期识别和针对性干预的必要性。通过在医疗治疗的同时优先提供心理支持,医疗服务提供者可以提高治疗效果,改善患者的长期生活质量。这种综合方法不仅可以优化临床结果,还可以减轻慢性伤口对更广泛的社会和经济影响。