Lovisetto P, Manachino D, Biarese V, Marchi L, Andrione P
Minerva Med. 1985 Jun 8;76(24):1113-22.
The most frequently observed of the symptomatic hypereosinophilias are those caused by allergic, cutaneous, parasitic, infectious, pulmonary and gastroenteric conditions. Among the allergic conditions, particular attention is paid to the hypereosinophilias caused by allergic asthma, gastroenteritis and reactions to drugs. The most common skin conditions linked to hypereosinophilias such as bullous dermatites and angio-oedema are considered. Turning to the parasitic conditions, the various types of parasite that may produce hypereosinophilias by infesting the organs are examined. The aetiology of tropical eosinophilias and the pathogenetic mechanism that may trigger hypereosinophilias are discussed. It has been thought advisable to group the lung pathologies associated with hypereosinophilias under a separate heading, despite the indubitable importance of the allergic element in these events. Among gastroenteric conditions, the one considered is eosinophilic gastroenteritis whose clinical, anatomopathological and aetiopathogenic features are still not quite clear. Examples of certain forms of secondary hypereosinophilias are given in the form of four unusual personal cases of bronchial asthma, filariasis, an exceptional infestation by Hypoderma bovis and eosinophilic gastroenteritis.
症状性嗜酸性粒细胞增多症中最常观察到的是由过敏、皮肤、寄生虫、感染、肺部和胃肠道疾病引起的那些。在过敏疾病中,特别关注由过敏性哮喘、肠胃炎和药物反应引起的嗜酸性粒细胞增多症。考虑了与嗜酸性粒细胞增多症相关的最常见皮肤疾病,如大疱性皮炎和血管性水肿。转向寄生虫疾病,研究了各种可能通过侵袭器官而导致嗜酸性粒细胞增多症的寄生虫类型。讨论了热带嗜酸性粒细胞增多症的病因以及可能引发嗜酸性粒细胞增多症的发病机制。尽管过敏因素在这些事件中具有毋庸置疑的重要性,但仍认为将与嗜酸性粒细胞增多症相关的肺部病变归为一个单独的类别是可取的。在胃肠道疾病中,所考虑的是嗜酸性粒细胞性肠胃炎,其临床、解剖病理学和病因发病学特征仍不太清楚。以4例不寻常的个人病例形式给出了某些形式的继发性嗜酸性粒细胞增多症的例子,这些病例分别为支气管哮喘、丝虫病、一例罕见的牛皮蝇幼虫感染和嗜酸性粒细胞性肠胃炎。