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Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Non-beneficial in Septic Shock.在判定硫胺素、维生素C加氢化可的松对感染性休克无益处之前，需要进行设计合理的研究。
Indian J Crit Care Med. 2025 Feb;29(2):191-192. doi: 10.5005/jp-journals-10071-24889. Epub 2025 Jan 31.
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Author Response: Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Nonbeneficial in Septic Shock.作者回复：在判定硫胺素、维生素C加氢化可的松对感染性休克无益处之前，需要进行设计合理的研究。
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Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial.维生素 C、氢化可的松和硫胺素与单独使用氢化可的松对感染性休克患者存活时间和脱离血管加压支持的影响：VITAMINS 随机临床试验。
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本文引用的文献

1
Evaluation of the Effects of a Combination of Vitamin C, Thiamine and Hydrocortisone vs Hydrocortisone Alone on ICU Outcome in Patients with Septic Shock: A Randomized Controlled Trial.维生素C、硫胺素和氢化可的松联合使用与单独使用氢化可的松对感染性休克患者重症监护病房结局影响的评估：一项随机对照试验
Indian J Crit Care Med. 2024 Dec;28(12):1147-1152. doi: 10.5005/jp-journals-10071-24852. Epub 2024 Nov 30.
2
Reevaluating vitamin C in sepsis and septic shock: a potential benefit in severe cases?重新评估败血症和感染性休克中的维生素C：对重症病例有潜在益处？
Front Med (Lausanne). 2024 Oct 29;11:1476242. doi: 10.3389/fmed.2024.1476242. eCollection 2024.
3
Vitamin C: Rationale for Its Use in Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS).维生素C：用于脓毒症诱导的急性呼吸窘迫综合征（ARDS）的理论依据。
Antioxidants (Basel). 2024 Jan 12;13(1):95. doi: 10.3390/antiox13010095.
4
Host-pathogen interactions in sepsis.脓毒症中的宿主-病原体相互作用
Lancet Infect Dis. 2008 Jan;8(1):32-43. doi: 10.1016/S1473-3099(07)70265-7. Epub 2007 Dec 11.

在判定硫胺素、维生素C加氢化可的松对感染性休克无益处之前，需要进行设计合理的研究。

Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Non-beneficial in Septic Shock.

作者信息

Finsterer Josef, Scorza Carla A, Scorza Fulvio A

机构信息

Department of Neurology, Neurology and Neurophysiology Center, Vienna, Austria.

Federal University of São Paulo (UNIFESP/EPM), São Paulo, Brazil.

出版信息

Indian J Crit Care Med. 2025 Feb;29(2):191-192. doi: 10.5005/jp-journals-10071-24889. Epub 2025 Jan 31.

DOI:10.5005/jp-journals-10071-24889
PMID:40110156
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11915438/
Abstract

Finsterer J, Scorza CA, Scorza FA. Appropriately Designed Studies are Needed before Thiamine and Vitamin C Plus Hydrocortisone are Judged Non-beneficial in Septic Shock. Indian J Crit Care Med 2025;29(2):191-192.

摘要

芬斯特勒 J、斯科尔扎 CA、斯科尔扎 FA。在判定硫胺素、维生素 C 加氢化可的松对感染性休克无益处之前，需要进行设计合理的研究。《印度重症监护医学杂志》2025 年；29(2)：191 - 192。