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用于静脉-肺体外膜肺氧合作为肺移植过渡的ProtekDuo套管:单中心病例系列

The ProtekDuo Cannula for Venopulmonary ECMO as Bridge to Lung Transplantation: A Single Center Case Series.

作者信息

Stukov Yuriy, Rackauskas Mindaugas, Maybauer Marc O

机构信息

Division of Thoracic Surgery, Department of Surgery, University of Florida, FL, USA.

Division of Critical Care Medicine, Department of Anesthesiology, University of Florida, FL, USA.

出版信息

Ann Card Anaesth. 2025 Apr 1;28(2):190-192. doi: 10.4103/aca.aca_194_24. Epub 2025 Mar 20.

DOI:10.4103/aca.aca_194_24
PMID:40110951
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12058063/
Abstract

Venovenous extracorporeal membrane oxygenation is the most commonly used mode of support in pre-lung transplant recipients. In patients who experience right ventricular dysfunction, venopulmonary ECMO is an excellent option to preserve RV function. We retrospectively reviewed patients who were supported with venopulmonary ECMO. Descriptive analysis, patient characteristics, ECMO outcomes, and survival were assessed. The primary outcome was mortality. Mean age was 45.5 ± 15.63, mean ECMO hours 1391.75 ± 1239.01. 4 patients had right ventricular dysfunction. All patients received bilateral orthotopic lung transplant. One-year survival was 100% for all patients. Venopulmonary extracorporeal membrane oxygenation can be safely used to bridge patients with end-stage lung disease to lung transplantation.

摘要

静脉-静脉体外膜肺氧合是肺移植术前受者最常用的支持模式。在出现右心室功能障碍的患者中,静脉-肺体外膜肺氧合是保留右心室功能的极佳选择。我们回顾性分析了接受静脉-肺体外膜肺氧合支持的患者。评估了描述性分析、患者特征、体外膜肺氧合结果和生存率。主要结局指标是死亡率。平均年龄为45.5±15.63岁,平均体外膜肺氧合时间为1391.75±1239.01小时。4例患者存在右心室功能障碍。所有患者均接受了双侧原位肺移植。所有患者的1年生存率为100%。静脉-肺体外膜肺氧合可安全用于将终末期肺病患者过渡到肺移植。

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本文引用的文献

1
Outcome of Veno-Pulmonary Extracorporeal Life Support in Lung Transplantation Using ProtekDuo Cannula: A Systematic Review and Description of Configurations.使用ProtekDuo插管进行肺移植的静脉-肺体外生命支持的结果:系统评价与配置描述
J Clin Med. 2024 Jul 14;13(14):4111. doi: 10.3390/jcm13144111.
2
Dual lumen venopulmonary extracorporeal membrane oxygenation cannulation technique using the ProtekDuo.使用ProtekDuo的双腔静脉-肺体外膜肺氧合插管技术。
Multimed Man Cardiothorac Surg. 2024 May 2;2024. doi: 10.1510/mmcts.2024.013.
3
The ProtekDuo in ECMO configuration for ARDS secondary to COVID-19: A systematic review.《COVID-19 继发急性呼吸窘迫综合征中使用 ProtekDuo 进行体外膜肺氧合的系统评价》。
Int J Artif Organs. 2023 Feb;46(2):93-98. doi: 10.1177/03913988221142904. Epub 2022 Dec 10.
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Acute right ventricular injury phenotyping in ARDS.急性呼吸窘迫综合征中的急性右心室损伤表型分析
Intensive Care Med. 2023 Jan;49(1):99-102. doi: 10.1007/s00134-022-06904-w. Epub 2022 Oct 11.
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Twenty-year experience with extracorporeal life support as bridge to lung transplantation.体外生命支持作为肺移植桥接的 20 年经验。
J Thorac Cardiovasc Surg. 2019 Jun;157(6):2515-2525.e10. doi: 10.1016/j.jtcvs.2019.02.048. Epub 2019 Feb 27.
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Acute respiratory distress syndrome.急性呼吸窘迫综合征。
Nat Rev Dis Primers. 2019 Mar 14;5(1):18. doi: 10.1038/s41572-019-0069-0.
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Outcomes of Extracorporeal Membrane Oxygenation as a Bridge to Lung Transplantation.体外膜肺氧合作为肺移植桥接的结果。
Ann Thorac Surg. 2019 May;107(5):1456-1463. doi: 10.1016/j.athoracsur.2019.01.032. Epub 2019 Feb 18.
8
How to minimise ventilator-induced lung injury in transplanted lungs: The role of protective ventilation and other strategies.如何将移植肺中的呼吸机相关性肺损伤降至最低:保护性通气及其他策略的作用
Eur J Anaesthesiol. 2015 Dec;32(12):828-36. doi: 10.1097/EJA.0000000000000291.