一例复杂的显微镜下多血管炎病例。

A Complicated Case of Granulomatosis with Polyangiitis.

作者信息

Gucev Filip, Bojadjioska Maja, Vidinikj Sonja, Sandevska Emilija, Petrova Sanja, Antova Dubravka, Vasilevska Ana, Vejseli Ron

机构信息

1University Clinic of Rheumatology, University "Ss. Cyril and Methodius", Skopje, RN Macedonia.

2University "Ss. Cyril and Methodius", Skopje, RN Macedonia.

出版信息

Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2025 Mar 21;46(1):45-52. doi: 10.2478/prilozi-2025-0005. Print 2025 Mar 1.

DOI:10.2478/prilozi-2025-0005

PMID:40116147

Abstract

Granulomatosis with polyangiitis, formerly known as Wegener's granulomatosis, is a condition often presenting with granulomatous vasculitis of both the upper and lower respiratory tracts together with glomerulonephritis. Here we present a case of a 17-year-old female patient, who presented with symptoms of pansinusitis with other symptoms gradually following. She was treated with cyclophosphamide which was later switched to rituximab and is now in remission.

摘要

肉芽肿性多血管炎，以前称为韦格纳肉芽肿病，是一种常表现为上、下呼吸道肉芽肿性血管炎并伴有肾小球肾炎的疾病。在此，我们报告一例17岁女性患者，该患者最初表现为全鼻窦炎症状，随后逐渐出现其他症状。她接受了环磷酰胺治疗，后来改用利妥昔单抗，目前病情缓解。