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脑肿瘤及脑肿瘤治疗的慢性神经并发症

Chronic Neurological Complications of Brain Tumors and Brain Tumor Treatments.

作者信息

Thakkar Jigisha P, Luy Diego D, Pickles Andrew, Refaat Tamer, Prabhu Vikram C

机构信息

Departments of Neurology and Neurological Surgery, Division of Neuro-Oncology, Loyola University Chicago Stritch School of Medicine, 2160 S. 1st Avenue Bldg 105, Room 2716, Maywood, IL, 60153, USA.

Department of Neurosurgery, Loyola University Medical Center, Maywood, IL, USA.

出版信息

Curr Neurol Neurosci Rep. 2025 Mar 21;25(1):26. doi: 10.1007/s11910-025-01411-z.

Abstract

PURPOSE OF REVIEW

Chronic complications of brain tumors and brain tumor treatments can lead to impairment of health-related quality of life and decreased functionality. These largely include cognitive decline, fatigue, headache, seizures, and secondary malignancies. Outpatient neurologists are an integral part of the multidisciplinary neuro-oncology team who help diagnose and manage chronic complications in this complex patient population. Timely diagnosis and treatment of these complications in outpatient neurology and neuro-oncology clinics helps improve quality of life and survival of brain tumor patients.

RECENT FINDINGS

We discuss updated information and management regarding various chronic neurologic complications among neuro-oncology patients. Understanding of chronic neurologic complications associated with central nervous system tumors and with common contemporary cancer treatments will facilitate neurologists management of these patient populations. While there are aspects analogous to the diagnosis and management in the non-oncologic population, a number of unique features discussed in this review should be considered.

摘要

综述目的

脑肿瘤及脑肿瘤治疗的慢性并发症可导致健康相关生活质量受损和功能下降。这些并发症主要包括认知衰退、疲劳、头痛、癫痫发作和继发性恶性肿瘤。门诊神经科医生是多学科神经肿瘤团队的重要组成部分,他们帮助诊断和管理这一复杂患者群体的慢性并发症。在门诊神经科和神经肿瘤诊所及时诊断和治疗这些并发症有助于提高脑肿瘤患者的生活质量和生存率。

最新发现

我们讨论了神经肿瘤患者各种慢性神经并发症的最新信息和管理方法。了解与中枢神经系统肿瘤及常见当代癌症治疗相关的慢性神经并发症将有助于神经科医生对这些患者群体进行管理。虽然在诊断和管理方面有一些与非肿瘤患者群体相似之处,但本综述中讨论的一些独特特征也应予以考虑。

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