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Non-Melanoma Skin Cancer Aggravation in Polycythemia Vera: Triggered by Ruxolitinib and Silenced With an IFN/Cemiplimab.

作者信息

Zafiriou Efterpi, Karampinis Emmanouil, Papadopoulos Vasileios, Stefani Georgia, Kotsakis Athanasios, Vassilopoulos George

机构信息

Department of Dermatology, Faculty of Medicine, School of Health Sciences, University General Hospital of Larissa, University of Thessaly, Larissa, Greece.

Department of Oncology, University General Hospital of Larissa, Larissa, Greece.

出版信息

Dermatol Pract Concept. 2025 Jan 30;15(1):4642. doi: 10.5826/dpc.1501a4642.

DOI:10.5826/dpc.1501a4642
PMID:40117636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11928117/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/11928117/7476e3453716/dc1501a4642g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/11928117/7476e3453716/dc1501a4642g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df54/11928117/7476e3453716/dc1501a4642g001.jpg

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Non-Melanoma Skin Cancer Aggravation in Polycythemia Vera: Triggered by Ruxolitinib and Silenced With an IFN/Cemiplimab.真性红细胞增多症中的非黑色素瘤皮肤癌加重:由鲁索替尼引发并通过干扰素/西米普利单抗得以缓解
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Real-world analysis of main clinical outcomes in patients with polycythemia vera treated with ruxolitinib or best available therapy after developing resistance/intolerance to hydroxyurea.羟基脲耐药/不耐受的真性红细胞增多症患者接受芦可替尼或最佳可用疗法治疗后的主要临床结局的真实世界分析。
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本文引用的文献

1
Combining PD-1/PD-L1 blockade with type I interferon in cancer therapy.将 PD-1/PD-L1 阻断与 I 型干扰素联合用于癌症治疗。
Front Immunol. 2023 Aug 24;14:1249330. doi: 10.3389/fimmu.2023.1249330. eCollection 2023.
2
A 10-year retrospective cohort study of ruxolitinib and association with nonmelanoma skin cancer in patients with polycythemia vera and myelofibrosis.一项关于芦可替尼与真性红细胞增多症和骨髓纤维化患者非黑色素瘤皮肤癌相关性的10年回顾性队列研究。
J Am Acad Dermatol. 2022 Feb;86(2):339-344. doi: 10.1016/j.jaad.2021.10.004. Epub 2021 Oct 11.