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在骨质疏松症高危患者中,特立帕肽治疗后的序贯治疗。

Sequential therapy following teriparatide treatment in patients at high risk of osteoporotic patients.

作者信息

Mori Satoshi

机构信息

Department of Bone and Joint Surgery, Osteoporosis Center, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.

出版信息

J Bone Miner Metab. 2025 Jan;43(1):22-25. doi: 10.1007/s00774-025-01584-0. Epub 2025 Mar 22.

DOI:10.1007/s00774-025-01584-0
PMID:40119935
Abstract

The use of medications in sequence is recommended in several osteoporosis guidelines to afford the best protection for the patient at very high risk of fracture. Sequential therapy following once-weekly as well as daily teriparatide treatment is a potent option for those patients.

摘要

在多个骨质疏松症指南中,推荐序贯使用药物,以便为骨折高风险患者提供最佳保护。对于这些患者而言,在每周一次以及每日一次的特立帕肽治疗之后进行序贯治疗是一种有效的选择。

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本文引用的文献

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Osteoporos Int. 2023 Jan;34(1):189-199. doi: 10.1007/s00198-022-06570-0. Epub 2022 Oct 14.
2
A randomized, controlled trial of once-weekly teriparatide injection versus alendronate in patients at high risk of osteoporotic fracture: primary results of the Japanese Osteoporosis Intervention Trial-05.一项每周一次特立帕肽注射与阿仑膦酸钠治疗骨质疏松性骨折高危患者的随机对照临床试验:日本骨质疏松干预试验-05 的主要结果。
Osteoporos Int. 2021 Nov;32(11):2301-2311. doi: 10.1007/s00198-021-05996-2. Epub 2021 May 17.
3
Development of the Asia Pacific Consortium on Osteoporosis (APCO) Framework: clinical standards of care for the screening, diagnosis, and management of osteoporosis in the Asia-Pacific region.亚太骨质疏松症联盟(APCO)框架的制定:亚太地区骨质疏松症筛查、诊断和管理的临床护理标准。
Osteoporos Int. 2021 Jul;32(7):1249-1275. doi: 10.1007/s00198-020-05742-0. Epub 2021 Jan 27.
4
Teriparatide Did Not Increase Adult Osteosarcoma Incidence in a 15-Year US Postmarketing Surveillance Study.特立帕肽在一项为期 15 年的美国上市后监测研究中未增加成人骨肉瘤的发病率。
J Bone Miner Res. 2021 Feb;36(2):244-251. doi: 10.1002/jbmr.4188. Epub 2020 Oct 13.
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Assessing the incidence of osteosarcoma among teriparatide users based on Medicare Part D and US State Cancer Registry Data.基于医疗保险处方数据库和美国州癌症登记处数据评估特立帕肽使用者中骨肉瘤的发病率。
Pharmacoepidemiol Drug Saf. 2020 Dec;29(12):1616-1626. doi: 10.1002/pds.5103. Epub 2020 Sep 7.
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