Vernon Marlo M, Datta Biplab, Coughlin Steven S
Augusta University, United States.
Augusta University, United States.
Cancer Epidemiol. 2025 Jun;96:102795. doi: 10.1016/j.canep.2025.102795. Epub 2025 Mar 23.
Patients with gynecologic cancers demonstrate different psychosocial outcomes based on their cancer site, which may affect treatment effectiveness and survivorship. Demographic differences and the relation with depression (DP) among women who have a gynecologic cancer diagnosis are not well understood.
To assess whether survivors of gynecologic cancer had a greater risk of DP compared with women with and without a history of cancer, 2020 BRFSS data was utilized. Pearson chi-square and multivariable logistic regression were conducted to obtain adjusted odds ratios.
Prevalence of DP was 20 % higher among survivors of gynecologic cancer; this was consistent across race/ethnic and urban/rural categories. Odds of DP among gynecologic cancer survivors were 2.5xs those without any history of cancer. Among Black and Hispanic gynecologic cancer survivors, the adjusted odds of DP were 4.5 and 3.2 times those with no cancer or a history of any cancer.
The odds of having DP were significantly higher among gynecologic cancer survivors compared to women without any history of cancer, breast cancer survivors, or survivors of other cancers.
妇科癌症患者根据其癌症部位表现出不同的心理社会结果，这可能会影响治疗效果和生存情况。妇科癌症诊断女性中的人口统计学差异及其与抑郁症（DP）的关系尚未得到充分了解。
为评估与有和没有癌症病史的女性相比，妇科癌症幸存者患DP的风险是否更高，使用了2020年行为风险因素监测系统（BRFSS）的数据。进行了Pearson卡方检验和多变量逻辑回归以获得调整后的优势比。
妇科癌症幸存者中DP的患病率高出20%；在种族/族裔和城市/农村类别中都是如此。妇科癌症幸存者患DP的几率是没有任何癌症病史者的2.5倍。在黑人及西班牙裔妇科癌症幸存者中，调整后的患DP几率分别是无癌症或任何癌症病史者的4.5倍和3.2倍。
与没有任何癌症病史的女性、乳腺癌幸存者或其他癌症幸存者相比，妇科癌症幸存者患DP的几率显著更高。
