Kimmig B, Brandeis W E, Eisenhut M, Bubeck B, Georgi P
Rontgenblatter. 1985 May;38(5):154-8.
The authors report on their experiences with metaiodine-benzylguanidine (MIBG) scintiscanning in a total of 36 patients. 7 of these patients had a benign pheochromocytoma, 4 a malignant one; neuroblastoma was seen in 10 patients. Scintiscan diagnosis was supplemented by measurements of irradiation exposure and attainable tumour dose. It was also shown that it is possible to mark neuroblastoma cells in cultures. The results of these studies are discussed and compared with those of other working groups. If the physiological pattern of distribution is taken into consideration, and if the proper imaging technique is adopted, MIBG scintiscan is a sensitive and highly specific method in diagnosing pheochromocytomas and neuroblastomas.
作者报告了他们对36例患者进行间碘苄胍（MIBG）闪烁扫描的经验。其中7例患者患有良性嗜铬细胞瘤，4例为恶性；10例患者患有神经母细胞瘤。通过测量辐射暴露和可达到的肿瘤剂量对闪烁扫描诊断进行补充。研究还表明，在培养物中标记神经母细胞瘤细胞是可行的。讨论了这些研究结果，并与其他研究小组的结果进行了比较。如果考虑到生理分布模式，并采用适当的成像技术，MIBG闪烁扫描是诊断嗜铬细胞瘤和神经母细胞瘤的一种敏感且高度特异的方法。
