Bentzon Thomas Takahashi, Abu-Khalil Maja, Venzo Alessandro, Matzen Dina Reem, Damsgaard Tina Engberg
Department of Plastic Surgery and Burns Treatment, Copenhagen University Hospital - Rigshospitalet.
Department of Clinical Medicine, University of Copenhagen.
Dan Med J. 2025 Jan 21;72(2):A08240522. doi: 10.61409/A08240522.
Immediate, implant-based breast reconstruction has become increasingly popular as a single-stage procedure with prepectoral placement of the implant following the introduction of biologic matrices. Only a few studies have described the use of bovine pericardium matrixTutomesh, a xenograft derived from bovine pericardium - and the use of laser-assisted indocyanine green angiography (ICG-A) to assess skin flap perfusion.
All patients who underwent a mastectomy followed by immediate reconstruction using prepectoral direct-to-implant with bovine pericardium from July 2019 to June 2021 were included. Complications were registered using the Clavien-Dindo classification. Postsurgical complications were analysed with multivariate logistic regression and feature selection.
A total of 81 prepectoral breast reconstructions were performed in 56 patients. The overall complication rate was 38.2%, and 14.3% required reoperation. Implant loss occurred in 3.7%. Multivariate logistic regression analysis demonstrated a statistically significant association between the risk of skin necrosis and previous breast surgery (p = 0.020) along with an increasing risk of implant rotation with increasing age (p = 0.010). The median follow-up was 9.9 months, and 11.1% of the breast reconstructions required postsurgical aesthetic correction.
Bovine pericardium may be used in prepectoral breast reconstruction with a good outcome. Careful patient selection is crucial, and ICG-A is helpful in reducing the risk of post-surgical complications.
None.
Not relevant.
随着生物基质的引入，即刻植入式乳房重建作为一种单阶段手术，在胸肌前植入假体越来越受欢迎。只有少数研究描述了牛心包基质Tutomesh（一种源自牛心包的异种移植物）的使用，以及使用激光辅助吲哚菁绿血管造影（ICG-A）来评估皮瓣灌注情况。
纳入2019年7月至2021年6月期间接受乳房切除术后采用胸肌前直接植入牛心包进行即刻重建的所有患者。使用Clavien-Dindo分类法记录并发症。通过多因素逻辑回归和特征选择分析术后并发症。
56例患者共进行了81次胸肌前乳房重建。总体并发症发生率为38.2%，14.3%的患者需要再次手术。假体丢失率为3.7%。多因素逻辑回归分析表明，皮肤坏死风险与既往乳房手术之间存在统计学显著关联（p = 0.020），并且随着年龄增长，假体旋转风险增加（p = 0.010）。中位随访时间为9.9个月，11.1%的乳房重建需要术后美学矫正。
牛心包可用于胸肌前乳房重建，效果良好。仔细的患者选择至关重要，ICG-A有助于降低术后并发症风险。
无。
不相关。
