Saini Bhawna, Gupta Ambika, Singh Harneet, Bisla Suman, Nagarajan Suriya, Kumia Komal
Department of Oral Medicine and Radiology, Faculty of Dental Science SGT University Budhera, 122505 Gurugram, India.
Department of Oral Medicine and Radiology, Post Graduate Institute of Dental Sciences, 124001 Rohtak, India.
J Oral Facial Pain Headache. 2025 Mar;39(1):81-92. doi: 10.22514/jofph.2025.007. Epub 2025 Mar 12.
Temporomandibular disorders associated myalgia (TMD-M) is one of the most common patient complaints in clinics. Because of the disease's multifactorial etiology and complexity,extensive understanding is required to determine an appropriate treatment protocol.
The current randomized comparison study included 80 patients who presented to the outpatient department with a TMD-M complaint. Patients were randomly assigned to one of two groups: continuous therapeutic ultrasound or pulsed therapeutic ultrasound, according to a standard protocol. The key outcome measures were pain intensity (visual analog scale (VAS), 0-10 cm) and muscle pressure pain threshold (PPT). Secondary outcome assessments included changes in maximal mouth opening, functional movements, and depression (Beck Depression Inventory (BDI)). A descriptive analysis was performed on the dataset to get data estimates for all variables.
The means of the differences in the two group's values were compared. Intergroup comparisons for normally distributed data were performed using independent sample -tests, and intragroup comparisons using repeated-measures Analysis of variance (ANOVA). For non-normally distributed data, such as pressure pain sensitivity (PPT), BDI, left laterotrusive movement (LLT), and protrusive movement (PM), intergroup comparisons were performed using the Mann-Whitney test, and intragroup comparisons using the Friedman test followed by the Wilcoxon signed-rank test. Although the intragroup changes in visual analogue scale (VAS) score, PPT, BDI, LLT and PM were highly significant in both groups ( < 0.001), there was no significant intergroup difference in pain reduction, PPT, BDI, LLT or PM ( > 0.05). There were no significant intergroup or intragroup differences in mouth opening or right lateral movement.
Both the pulse and continuous modes of therapeutic ultrasound (US) are equally effective in relieving pain. US therapy in both modes is a potent and independent therapeutic modality for the treatment of TMD-M.
NCT05211245.
颞下颌关节紊乱相关肌痛（TMD-M）是临床最常见的患者主诉之一。由于该疾病病因多因素且复杂，需要深入了解以确定合适的治疗方案。
当前的随机对照研究纳入了80例因TMD-M主诉前来门诊就诊的患者。根据标准方案，患者被随机分为两组：连续治疗性超声组或脉冲治疗性超声组。主要结局指标为疼痛强度（视觉模拟评分法（VAS），0-10厘米）和肌肉压痛阈值（PPT）。次要结局评估包括最大开口度、功能运动和抑郁（贝克抑郁量表（BDI））的变化。对数据集进行描述性分析以获得所有变量的数据估计值。
比较两组数值差异的均值。对于正态分布数据，组间比较采用独立样本t检验，组内比较采用重复测量方差分析（ANOVA）。对于非正态分布数据，如压痛敏感性（PPT）、BDI、左侧侧方运动（LLT）和前伸运动（PM），组间比较采用曼-惠特尼检验，组内比较采用弗里德曼检验，随后进行威尔科克森符号秩检验。尽管两组的视觉模拟量表（VAS）评分、PPT、BDI、LLT和PM的组内变化均具有高度显著性（<0.001），但在疼痛减轻、PPT、BDI、LLT或PM方面组间无显著差异（>0.05）。开口度或右侧侧方运动方面组间和组内均无显著差异。
治疗性超声（US）的脉冲和连续模式在缓解疼痛方面同样有效。两种模式的US治疗都是治疗TMD-M的有效且独立的治疗方式。
NCT05211245。
