Yang Zhili, Lu Jiejie, Li Zhen
Department of Dermatology, The Fifth People's Hospital of Hainan Province, Haikou, Hainan, People's Republic of China.
Clin Cosmet Investig Dermatol. 2025 Mar 20;18:663-668. doi: 10.2147/CCID.S517299. eCollection 2025.
Generalized Pustular Psoriasis (GPP) is a recurrent dermatological condition characterized by widespread erythematous plaques, scaling, and sterile pustules. Notably, in a subset of patients, these lesions manifest exclusively in localized areas. We report a case where abrocitinib was used to treat the localized type of GPP, achieving relatively good clinical efficacy and without obvious side effects. To date, there are no published reports on the use of abrocitinib for GPP treatment, either domestically or internationally, making this case a valuable reference for clinicians and researchers.
泛发性脓疱型银屑病（GPP）是一种复发性皮肤病，其特征为广泛的红斑、鳞屑和无菌性脓疱。值得注意的是，在一部分患者中，这些皮损仅局限于局部区域。我们报告了一例使用阿布昔替尼治疗局限性GPP的病例，取得了相对较好的临床疗效且无明显副作用。迄今为止，国内外均无关于使用阿布昔替尼治疗GPP的报道，该病例为临床医生和研究人员提供了有价值的参考。
