The Role of Basement Membrane Thickening in Airway Physiology and Immunopathology of Severe Asthma.
作者信息
Liu Matthew H, Hallstrand Teal S
机构信息
University of Washington Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Seattle, Washington, United States.
University of Washington Department of Medicine, Medicine, Seattle, Washington, United States;
出版信息
Am J Respir Crit Care Med. 2025 Mar 25;211(5):676-7. doi: 10.1164/rccm.202502-0365ED.
Abstract
摘要
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本文引用的文献
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Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma.哮喘患者气道高反应性的基础是不同的上皮-先天免疫细胞转录回路。
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Airway hyperresponsiveness reflects corticosteroid-sensitive mast cell involvement across asthma phenotypes.气道高反应性反映了跨哮喘表型的皮质类固醇敏感肥大细胞的参与。
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Identification of mast cell progenitor cells in the airways of individuals with allergic asthma.在过敏性哮喘患者气道中鉴定肥大细胞祖细胞。
Allergy. 2023 Feb;78(2):547-549. doi: 10.1111/all.15498. Epub 2022 Sep 12.
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Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.气道壁中嗜酸性粒细胞的位置对于哮喘气道高反应性和 T2 炎症的特定特征至关重要。
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