Bayu Tewodros Mekonin, Sisay Assefa Legesse, Kebede Ayantu
Arsi University, Assela, Ethiopia
Arsi University, Assela, Ethiopia.
BMJ Open. 2025 Mar 24;15(3):e087368. doi: 10.1136/bmjopen-2024-087368.
To determine the time to recovery from severe pneumonia and its predictors in children aged 2-59 months admitted to the Asella Referral and Teaching Hospital, Ethiopia.
DESIGN, PARTICIPANTS, AND SETTING: An institution-based retrospective cohort study was conducted on 424 children aged 2-59 months in Asella Town, Ethiopia. Medical records of eligible children were selected using a simple random sampling technique. The Kaplan-Meier curve and log-rank test were used to describe the survival function. Independent predictors of recovery time were identified using Cox regression analysis. The 95% CI of the HR with a corresponding p value of 0.05 was used to declare statistical significance.
Recovery time from severe pneumonia and its predictors.
The median recovery time was 5 days. The incidence density of recovery was 16 (95% CI: 14.44 to 17.76) per 100-person-day observation. Being a rural resident (adjusted HR (AHR): 0.68; 95% CI: 0.57 to 0.82), aged 36-59 months (AHR: 0.70; 95% CI: 0.50 to 0.98), being underweight (AHR: 0.75; 95% CI: 0.59 to 0.95), the presence of danger signs (AHR: 0.31; 95% CI: 0.24 to 0.39) and having comorbidity (AHR: 0.38; 95% CI: 0.30 to 0.48) were significant predictors of time to recovery in children aged 2-59 months.
In this study, the median recovery time was longer than that reported in similar studies. Age, residence, underweight, danger signs and comorbidities were significant predictors. Therefore, families of children with identified predictors need counselling to prepare for the likelihood of slow recovery.
确定埃塞俄比亚阿塞拉转诊与教学医院收治的2至59个月大儿童从重症肺炎中康复的时间及其预测因素。
设计、研究对象与研究地点:在埃塞俄比亚阿塞拉镇对424名2至59个月大的儿童进行了一项基于机构的回顾性队列研究。采用简单随机抽样技术选取符合条件儿童的病历。使用Kaplan-Meier曲线和对数秩检验来描述生存函数。采用Cox回归分析确定康复时间的独立预测因素。使用HR的95%置信区间及相应p值为0.05来判定统计学显著性。
从重症肺炎中康复的时间及其预测因素。
中位康复时间为5天。每100人日观察的康复发病密度为16(95%置信区间:14.44至17.76)。农村居民(调整后HR(AHR):0.68;95%置信区间:0.57至0.82)、年龄在36至59个月(AHR:0.70;95%置信区间:0.50至0.98)、体重不足(AHR:0.75;95%置信区间:0.59至0.95)、存在危险体征(AHR:0.31;95%置信区间:0.24至0.39)以及患有合并症(AHR:0.38;95%置信区间:0.30至0.48)是2至59个月大儿童康复时间的显著预测因素。
在本研究中,中位康复时间长于类似研究报告的时间。年龄、居住地、体重不足、危险体征和合并症是显著的预测因素。因此,对有已确定预测因素的儿童家庭需要进行咨询,使其为康复可能较慢做好准备。