Ren Yuan, Zhu Xiaohui, Zhang Lu, Kang Cheng, Wang Kai
Department of Otolaryngology, Ningbo No.2 Hospital, Ningbo, 315000, Zhejiang, China.
Health Science Center, Ningbo University, Ningbo, Zhejiang, China.
Sci Rep. 2025 Mar 25;15(1):10206. doi: 10.1038/s41598-025-95378-z.
To evaluate the prognostic significance of aditus ad antrum patency, as determined by computed tomography (CT), on the surgical outcomes in patients with chronic suppurative otitis media (CSOM). This study analyzed CSOM patients who had tympanoplasty at a tertiary hospital from 2015 to 2019. Patient demographics, operative reports, preoperative CT scans and outcomes were reviewed. Aditus ad antrum patency was evaluated on CT images. Outcome measures included graft success and postoperative air-bone gap (ABG) at the last follow-up (≥ 6 months). During the study, 138 patients with CSOM patients were included. Computed tomography (CT) scans revealed a blocked aditus in 37 patients (26.8%). Patients in the patent aditus group demonstrated a significantly better hearing prognosis compared to those in the obstructed aditus group (P = 0.002). In the low- and intermediate-risk subgroups, patients with a blocked aditus exhibited significantly poorer postoperative hearing outcomes compared to those with a patent aditus (P < 0.001). Multivariate logistic regression analysis identified obstructed aditus ad antrum (OR 1.83, 95% CI 1.10-3.04; P = 0.020) and a Middle Ear Risk Index (MERI) score greater than 3 (OR 2.68, 95% CI 1.06-6.75; P = 0.037) as independent adverse prognostic factors for hearing success in patients with CSOM. A patent aditus ad antrum correlates with preoperative dry ear, no middle ear granulation, a well-pneumatized mastoid, and a low MERI score. Preoperative CT showing aditus ad antrum patency may independently predict hearing outcomes and help stratify risk in CSOM patients.
为评估通过计算机断层扫描(CT)确定的鼓窦入口通畅情况对慢性化脓性中耳炎(CSOM)患者手术结局的预后意义。本研究分析了2015年至2019年在一家三级医院接受鼓室成形术的CSOM患者。回顾了患者的人口统计学资料、手术报告、术前CT扫描及结局。在CT图像上评估鼓窦入口通畅情况。结局指标包括移植物成功率及最后一次随访(≥6个月)时的术后气骨导差(ABG)。研究期间,纳入了138例CSOM患者。计算机断层扫描(CT)显示37例患者(26.8%)的鼓窦入口堵塞。鼓窦入口通畅组患者的听力预后明显优于鼓窦入口堵塞组(P = 0.002)。在低风险和中等风险亚组中,鼓窦入口堵塞的患者术后听力结局明显比鼓窦入口通畅的患者差(P < 0.001)。多因素逻辑回归分析确定鼓窦入口堵塞(比值比1.83,95%可信区间1.10 - 3.04;P = 0.020)和中耳风险指数(MERI)评分大于3(比值比2.68,95%可信区间1.06 - 6.75;P = 0.037)是CSOM患者听力成功的独立不良预后因素。鼓窦入口通畅与术前干耳、无中耳肉芽、乳突气房良好及MERI评分低相关。术前CT显示鼓窦入口通畅可能独立预测听力结局并有助于对CSOM患者进行风险分层。