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[放线菌病患者和健康供体中受放线菌溶解产物影响的白细胞形成玫瑰花结能力的变化]

[Changes in the leukocyte capacity for rosette formation as affected by actinolysate in actinomycosis patients and healthy donors].

作者信息

Robustova T G, Kostishin I D, Poniakina I D, Sosnovskiĭ A L, Kats A G

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1985 Apr(4):33-5.

PMID:4013571
Abstract

The action of actinolysate on the capacity of lymphocytes and neutrophils for rosette-formation has been studied in patients with actinomycosis of the maxillofacial area and with chronic nonspecific inflammatory processes, as well as in healthy donors. Actinolysate has been found to have different influence on cell activity. In actinomycosis patients with the low capacity of cells for spontaneous E-rosette-formation with sheep red blood cells (SRBC) actinolysate suppresses their activity still greater, while in cases of the high capacity of cells for spontaneous epsilon-rosette-formation with SRBC this capacity is increased. In chronic nonspecific inflammatory processes in the maxillofacial area and in healthy donors the reverse tendency is observed.

摘要

已对颌面部放线菌病患者、患有慢性非特异性炎症过程的患者以及健康供体研究了放线菌溶解产物对淋巴细胞和中性粒细胞形成玫瑰花结能力的作用。已发现放线菌溶解产物对细胞活性有不同影响。在细胞与绵羊红细胞(SRBC)自发形成E玫瑰花结能力较低的放线菌病患者中,放线菌溶解产物对其活性的抑制作用更强,而在细胞与SRBC自发形成ε玫瑰花结能力较高的情况下,这种能力会增强。在颌面部慢性非特异性炎症过程中以及健康供体中观察到相反的趋势。

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