带状疱疹：发生、并发症及复发的危险因素，重点关注免疫功能低下患者
Herpes Zoster: Risk Factors for Occurrence, Complications, and Recurrence with a Focus on Immunocompromised Patients.
作者信息
Oleszko Michał, Zapolnik Paweł, Kmiecik Wojciech, Czajka Hanna
机构信息
College of Medical Sciences, University of Rzeszów, 35-315 Rzeszów, Poland.
St. Louis Provincial Specialist Children's Hospital, 31-503 Kraków, Poland.
出版信息
Diseases. 2025 Feb 26;13(3):71. doi: 10.3390/diseases13030071.
BACKGROUND
The varicella-zoster virus is a highly contagious human herpesvirus that primarily causes varicella (chickenpox) as an initial infection, targeting T cells, neurons, as well as skin cells, and can later reactivate to cause herpes zoster (shingles). Following reactivation, the varicella-zoster virus infection can lead to severe complications, the most common of which is postherpetic neuralgia. Risk factors include aging, immunosuppression, chronic diseases such as diabetes, cardiovascular disorders, respiratory conditions, and others.
OBJECTIVE
In this article, we present an analysis of factors increasing the risk of herpes zoster occurrence, complications, and recurrences (in particular in immunocompromised patients).
背景
水痘带状疱疹病毒是一种高度传染性的人类疱疹病毒，初次感染主要引起水痘，靶向T细胞、神经元以及皮肤细胞，随后可重新激活引发带状疱疹。重新激活后，水痘带状疱疹病毒感染可导致严重并发症，其中最常见的是带状疱疹后神经痛。危险因素包括年龄增长、免疫抑制、糖尿病等慢性疾病、心血管疾病、呼吸系统疾病等。
目的
在本文中，我们对增加带状疱疹发生、并发症及复发风险的因素（尤其是免疫功能低下患者）进行分析。
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