Suppr超能文献

生物可吸收缝线锚钉的生物力学特性比较:一项综述

Comparing Biomechanical Properties of Bioabsorbable Suture Anchors: A Comprehensive Review.

作者信息

Schonebaum Dorien I, Garbaccio Noelle, Escobar-Domingo Maria J, Wood Sasha, Smith Jade E, Foster Lacey, Mehdizadeh Morvarid, Cordero Justin J, Foppiani Jose A, Choudry Umar, Kaplan David L, Lin Samuel J

机构信息

Department of Plastic and Reconstructive Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

Department of Plastic and Reconstructive Surgery, Amsterdam UMC, 1105 AZ Amsterdam, The Netherlands.

出版信息

Biomimetics (Basel). 2025 Mar 12;10(3):175. doi: 10.3390/biomimetics10030175.

Abstract

Suture anchors (SAs) are medical devices used to connect soft tissue to bone. Traditionally these were made of metal; however, in the past few decades, bio-absorbable suture anchors have been created to overcome revision surgeries and other complications caused by metallic SAs. This systematic review aims to analyze the biomechanical properties of these SAs to gain a better understanding of their safety and utilization. A comprehensive systematic review that adhered to the PRISMA guidelines was conducted. Primary outcomes were that the pull-out strength of SAs, the rate of degradation secondarily, and the biocompatibility of all SAs were analyzed. After screening 347 articles, 16 were included in this review. These studies revealed that the pull-out strength of bio-absorbable SAs was not inferior to that of their non-absorbable comparatives. The studies also revealed that the rate of degradation varies widely from 7 to 90 months. It also showed that not all absorbable SAs were fully absorbed within the expected timeframe. This systematic review demonstrates that existing suture anchor materials exhibit comparable pull-out strengths, material-specific degradation rates, and variable biocompatibility. All-suture anchors had promising results in biocompatibility, but evidence fails to identify a single most favorable material. Higher-powered studies that incorporate tissue-specific characteristics, such as rotator cuff tear size, are warranted. To meet demonstrated shortcomings in strength and biocompatibility, we propose silk fibroin as a novel material for suture anchor design for its customizable properties and superior strength.

摘要

缝合锚钉(SAs)是用于将软组织连接到骨骼的医疗器械。传统上,这些是由金属制成的;然而,在过去几十年中,已经研发出生物可吸收缝合锚钉,以克服由金属缝合锚钉引起的翻修手术和其他并发症。本系统评价旨在分析这些缝合锚钉的生物力学性能,以便更好地了解其安全性和应用情况。进行了一项遵循PRISMA指南的全面系统评价。主要结果是分析了缝合锚钉的拔出强度、其次是降解速率以及所有缝合锚钉的生物相容性。在筛选了347篇文章后,本评价纳入了16篇。这些研究表明,生物可吸收缝合锚钉的拔出强度并不低于其不可吸收对照物。研究还表明,降解速率差异很大,从7个月到90个月不等。研究还表明,并非所有可吸收缝合锚钉都在预期时间内完全吸收。本系统评价表明,现有的缝合锚钉材料具有可比的拔出强度、特定材料的降解速率和可变的生物相容性。所有缝合锚钉在生物相容性方面都有良好的结果,但证据未能确定单一最有利的材料。有必要开展纳入组织特异性特征(如肩袖撕裂大小)的更高效能研究。为了弥补在强度和生物相容性方面已证明的不足,我们提出将丝素蛋白作为一种用于缝合锚钉设计的新型材料,因为它具有可定制的特性和卓越的强度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/64c4/11940533/214901206342/biomimetics-10-00175-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验