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Complement Inhibition Therapy in IgA Nephropathy: Total or Selective Inhibition?

作者信息

Zhu Zhiyong, Zhang Chengcai, Wang Hongyun, Li Baozhen

机构信息

Department of Nephrology, Zibo Central Hospital, Zibo, China.

Department of Gastrointestinal Surgery, Zibo Central Hospital, Zibo, China.

出版信息

J Am Soc Nephrol. 2025 May 1;36(5):984-985. doi: 10.1681/ASN.0000000673. Epub 2025 Mar 26.

DOI:10.1681/ASN.0000000673
PMID:40137582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12059083/
Abstract
摘要

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Authors' Reply: Complement Inhibition Therapy in IgA Nephropathy: Total or Selective Inhibition?作者回复:IgA肾病中的补体抑制疗法:完全抑制还是选择性抑制?
J Am Soc Nephrol. 2025 May 1;36(5):986-987. doi: 10.1681/ASN.0000000674. Epub 2025 Mar 26.
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Successful Remission of Nephrotic Syndrome Caused by IgA Nephropathy with Membranoproliferative Glomerulonephritis-pattern Lesion Treated by Cyclosporine and Oral Corticosteroids.环孢素与口服糖皮质激素治疗IgA肾病伴膜增生性肾小球肾炎样病变所致肾病综合征成功缓解
Intern Med. 2025 Jul 10. doi: 10.2169/internalmedicine.5526-25.

引用本文的文献

1
Authors' Reply: Complement Inhibition Therapy in IgA Nephropathy: Total or Selective Inhibition?作者回复:IgA肾病中的补体抑制疗法:完全抑制还是选择性抑制?
J Am Soc Nephrol. 2025 May 1;36(5):986-987. doi: 10.1681/ASN.0000000674. Epub 2025 Mar 26.

本文引用的文献

1
Efficacy and Safety of Ravulizumab in IgA Nephropathy: A Phase 2 Randomized Double-Blind Placebo-Controlled Trial.ravulizumab治疗IgA肾病的疗效与安全性:一项2期随机双盲安慰剂对照试验
J Am Soc Nephrol. 2025 Apr 1;36(4):645-656. doi: 10.1681/ASN.0000000534. Epub 2024 Oct 25.
2
Alternative Complement Pathway Inhibition with Iptacopan in IgA Nephropathy.Iptacopan对替代补体途径的抑制作用在IgA肾病中的研究
N Engl J Med. 2025 Feb 6;392(6):531-543. doi: 10.1056/NEJMoa2410316. Epub 2024 Oct 25.
3
IgA nephropathy: the lectin pathway and implications for targeted therapy.IgA 肾病:凝集素途径及其对靶向治疗的意义。
Kidney Int. 2023 Aug;104(2):254-264. doi: 10.1016/j.kint.2023.04.029. Epub 2023 May 30.
4
Deposition of the Membrane Attack Complex in Healthy and Diseased Human Kidneys.健康和患病人类肾脏中膜攻击复合物的沉积。
Front Immunol. 2021 Feb 11;11:599974. doi: 10.3389/fimmu.2020.599974. eCollection 2020.
5
Complement in IgA Nephropathy: The Role of Complement in the Pathogenesis, Diagnosis, and Future Management of IgA Nephropathy.补体在 IgA 肾病中的作用:补体在 IgA 肾病发病机制、诊断和未来管理中的作用。
Adv Chronic Kidney Dis. 2020 Mar;27(2):111-119. doi: 10.1053/j.ackd.2019.12.004.
6
The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy.补体蛋白作为 IgA 肾病治疗靶点的新作用。
Front Immunol. 2019 Mar 19;10:504. doi: 10.3389/fimmu.2019.00504. eCollection 2019.