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直立性低血压老年受试者对葡萄糖摄入的自主神经反应。

Autonomic responses to glucose ingestion in elderly subjects with orthostatic hypotension.

作者信息

Robinson B J, Johnson R H, Lambie D G, Palmer K T

出版信息

Age Ageing. 1985 May;14(3):168-73. doi: 10.1093/ageing/14.3.168.

DOI:10.1093/ageing/14.3.168
PMID:4013904
Abstract

The cardiovascular and plasma catecholamine responses to oral glucose (50 g) ingestion were investigated in five elderly subjects with orthostatic hypotension and five elderly control subjects. All the orthostatic hypotension subjects showed blood pressure falls after glucose ingestion, as compared to only one of the control subjects. Significantly greater falls in the orthostatic hypotension as compared to control patients were observed for systolic blood pressure (P less than 0.01) at 60 and 90 min following glucose and mean blood pressure (P less than 0.05) at 60 min following glucose. The orthostatic hypotension subjects did not have evidence of reduced heart-rate or plasma catecholamine responses to the glucose ingestion. It is concluded that, in elderly patients with orthostatic hypotension, disorder of blood pressure control may also cause hypotension associated with eating.

摘要

对五名患有体位性低血压的老年受试者和五名老年对照受试者进行了口服葡萄糖(50克)摄入后心血管和血浆儿茶酚胺反应的研究。与仅一名对照受试者相比,所有体位性低血压受试者在摄入葡萄糖后均出现血压下降。在摄入葡萄糖后60分钟和90分钟时,体位性低血压受试者的收缩压较对照患者显著下降(P<0.01),在摄入葡萄糖后60分钟时平均血压也显著下降(P<0.05)。体位性低血压受试者没有证据表明对葡萄糖摄入的心率或血浆儿茶酚胺反应降低。得出的结论是,在患有体位性低血压的老年患者中,血压控制紊乱也可能导致与进食相关的低血压。

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Autonomic responses to glucose ingestion in elderly subjects with orthostatic hypotension.直立性低血压老年受试者对葡萄糖摄入的自主神经反应。
Age Ageing. 1985 May;14(3):168-73. doi: 10.1093/ageing/14.3.168.
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Autonomic responses to carbohydrate ingestion and head-up tilt in elderly subjects with orthostatic hypotension.直立性低血压老年受试者对碳水化合物摄入和头高位倾斜的自主神经反应。
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The effect of caffeine on postprandial blood pressure in the frail elderly.咖啡因对体弱老年人餐后血压的影响。
Postgrad Med J. 1991 Jun;67(788):543-7. doi: 10.1136/pgmj.67.788.543.
2
Autonomic responses to carbohydrate ingestion and head-up tilt in elderly subjects with orthostatic hypotension.直立性低血压老年受试者对碳水化合物摄入和头高位倾斜的自主神经反应。
Clin Auton Res. 1992 Oct;2(5):309-16. doi: 10.1007/BF01824301.