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[神经源性膀胱患儿膀胱输尿管反流的管理——抗反流手术的回顾性研究]

[Management of vesicoureteral reflux in children with neurogenic bladder--retrospective studies of antireflux surgery].

作者信息

Sakurai T, Nakamura M, Tsuzimoto Y, Sugao H

出版信息

Hinyokika Kiyo. 1985 Feb;31(2):257-63.

PMID:4013944
Abstract

During the last 3.5 years, 18 children and 9 adults with vesicoureteral reflux and neurogenic bladder dysfunction were seen at our hospital, and 11 children and 4 adults required antireflux surgery. The criteria of repair were progressive renal deterioration and/or uncontrollable urinary infection. Surgery was applied mainly to the conditions of detrusor hyperreflexia and/or lower urinary tract obstruction. The combined technique of Politano-Leadbetter and Glenn-Anderson was used in 8 children and 3 adults, and the Cohen technique was used in 3 children and 1 adult. Surgery was successful that is, cessation of reflux and no obstruction, was achieved in all but one patient, who had received radical hysterectomy previously. Though recurrent episodes of lower urinary tract infection persisted in some cases after operation, over-all usage of antibiotics was reduced. Seven children with reflux and uninhibited bladder, though some of them with high grade reflux, were managed successfully by anticholinergic drug or transcutaneous electrical stimulation.

摘要

在过去的3.5年里,我院共接诊了18名患有膀胱输尿管反流和神经源性膀胱功能障碍的儿童以及9名成人,其中11名儿童和4名成人需要进行抗反流手术。手术修复的标准是进行性肾脏恶化和/或无法控制的泌尿系统感染。手术主要针对逼尿肌反射亢进和/或下尿路梗阻的情况。8名儿童和3名成人采用了波利塔诺-利德贝特(Politano-Leadbetter)和格伦-安德森(Glenn-Anderson)联合技术,3名儿童和1名成人采用了科恩(Cohen)技术。除1例曾接受过根治性子宫切除术的患者外,所有患者手术均成功,即实现了反流停止且无梗阻。尽管术后部分病例仍有下尿路感染反复发作,但抗生素的总体使用量减少了。7名患有反流和无抑制性膀胱的儿童,尽管其中一些患有高级别反流,但通过抗胆碱能药物或经皮电刺激成功得到了治疗。

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