Miura T, Sakuramoto T, Noguchi S, Shuin T, Moriyama M, Kubota Y
Hinyokika Kiyo. 1985 Feb;31(2):265-71.
Fifty-seven patients with low-grade and low-stage urinary bladder cancer were treated at our University Hospital between 1970 and 1980. The incidence of low grade and low stage cases was higher in the young group than in the older group, and in male than in female (p less than 0.05). Most of the patients were well-controlled by either TUR or other conservative therapies. The 5-year relative survival rate was 113%. The 5-year actual cumulative recurrence rate after TUR was 63%, whereas, the 5-year actual cumulative recurrence rate was only 35.4% in those who received intravesical instillation therapy and 25% in those who undergone RCH (Radio-Chemo-Hyperthermia) therapy. Five patients (9%) showed an increase of tumor grade from low to intermediate at the time of intravesical recurrence, but no patient showed a change from low to high grade.
1970年至1980年间，我校医院共治疗了57例低级别、低分期的膀胱癌患者。低级别、低分期病例在年轻组中的发病率高于老年组，男性高于女性（p<0.05）。大多数患者通过经尿道切除术（TUR）或其他保守治疗得到了良好控制。5年相对生存率为113%。TUR术后5年实际累积复发率为63%，而接受膀胱内灌注治疗的患者5年实际累积复发率仅为35.4%，接受放射化学热疗（RCH）的患者为25%。5例患者（9%）在膀胱内复发时肿瘤分级从低级别升至中级别，但没有患者从低级别变为高级别。
