Suppr超能文献

八旬老人症状性颅外颈动脉支架置入术的结局:一项关于再狭窄、危险因素和并发症的单中心回顾性研究

Outcomes of Symptomatic Extracranial Carotid Artery Stenting in Octogenarians: A Single-Center Retrospective Study on Restenosis, Risk Factors, and Complications.

作者信息

Ertuğrul Özgür Zülfükar, Karaaslan Fırat, Yılmaz Reşit, Tuncer Mehmet Cudi

机构信息

Department of Radiology, Gazi Yaşargil Training and Research Hospital, University of Health Sciences, Diyarbakır 21090, Turkey.

Department of Neurology, Gazi Yaşargil Training and Research Hospital, University of Health Sciences, Diyarbakır 21090, Turkey.

出版信息

Medicina (Kaunas). 2025 Mar 17;61(3):519. doi: 10.3390/medicina61030519.

Abstract

This study aimed to evaluate the 6-month restenosis rate, risk factors, and complications following carotid artery stenting (CAS) in patients aged 80 years and older, assessing the efficacy and safety of CAS in this population. Fifty-six patients aged ≥80 years with symptomatic extracranial carotid stenosis who underwent CAS between May 2023 and August 2024 were retrospectively analyzed. Follow-up at 6 months included Doppler ultrasonography to assess restenosis. Demographic, clinical, and procedure-related complications were recorded, and risk factors for in-stent restenosis were evaluated. Among the patients, 42.9% were female (n = 24) and 57.1% were male (n = 32), with a mean age of 85.3 ± 4.40 years. The restenosis rate was 12.5%. Restenosis was significantly associated with smoking ( = 0.002), severe stenosis ( = 0.016), and advanced age ( = 0.045). The minor complication rate was 5.3%, and no major complications were observed. Smoking and advanced age were identified as independent risk factors for restenosis. CAS is a safe and effective treatment option for elderly patients. However, those with a history of smoking, advanced age, or severe stenosis are at an increased risk of restenosis. These findings provide valuable insights into the outcomes and safety of CAS in patients aged 80 and older.

摘要

本研究旨在评估80岁及以上患者颈动脉支架置入术(CAS)后6个月的再狭窄率、危险因素及并发症,以评估CAS在该人群中的疗效和安全性。对2023年5月至2024年8月期间接受CAS治疗的56例年龄≥80岁的有症状颅外颈动脉狭窄患者进行回顾性分析。6个月时的随访包括用多普勒超声评估再狭窄情况。记录人口统计学、临床及与手术相关的并发症,并评估支架内再狭窄的危险因素。患者中,42.9%为女性(n = 24),57.1%为男性(n = 32),平均年龄为85.3±4.40岁。再狭窄率为12.5%。再狭窄与吸烟(P = 0.002)、严重狭窄(P = 0.016)和高龄(P = 0.045)显著相关。轻微并发症发生率为5.3%,未观察到严重并发症。吸烟和高龄被确定为再狭窄的独立危险因素。CAS是老年患者安全有效的治疗选择。然而,有吸烟史、高龄或严重狭窄的患者再狭窄风险增加。这些发现为80岁及以上患者CAS的治疗结果和安全性提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d08a/11943715/53db4da269c7/medicina-61-00519-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验