Kubiak Kinga, Bazylewicz-Zakrzewska Katarzyna, Poncyljusz Wojciech
Department of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University in Szczecin, 71-252 Szczecin, Poland.
J Clin Med. 2025 Mar 12;14(6):1900. doi: 10.3390/jcm14061900.
: Pulmonary embolism is a potentially life-threatening condition caused by the sudden occlusion of pulmonary arteries. Its non-specific and highly variable clinical presentation often leads to undiagnosed cases, making computed tomography pulmonary angiography (CTPA) essential for diagnosis. Hampton's hump is a rare radiological finding associated with pulmonary embolism, characterized by a wedge-shaped, pleural-based opacification due to pulmonary infarction. : This study examines the correlation between pulmonary embolism severity and the presence of Hampton's hump in CTPA based on a database of 428 patients. : We observed a correlation between the presence of Hampton's hump and an increased likelihood of rider-type embolism, pleural effusion, and dilation of the pulmonary trunk and left pulmonary artery. The data indicate that patients with at least one risk factor for severe pulmonary embolism are more likely to present with Hampton's hump. Furthermore, the presence of this sign in patients diagnosed with pulmonary embolism and pleural effusion substantially increases the risk of in-hospital death. : This study underscores the significance of Hampton's hump as a rare but clinically relevant radiological finding in patients with pulmonary embolism. Given the limited number of studies on this topic, our findings provide valuable insights into the role of Hampton's hump in the context of pulmonary embolism.
肺栓塞是一种由肺动脉突然阻塞引起的潜在危及生命的疾病。其非特异性且高度可变的临床表现常常导致病例漏诊，这使得计算机断层扫描肺动脉造影（CTPA）成为诊断的关键。汉普顿驼峰是一种与肺栓塞相关的罕见影像学表现，其特征为因肺梗死导致的楔形、胸膜下致密影。：本研究基于428例患者的数据库，探讨了CTPA中肺栓塞严重程度与汉普顿驼峰的存在之间的相关性。：我们观察到汉普顿驼峰的存在与骑跨型栓塞、胸腔积液以及肺动脉主干和左肺动脉扩张的可能性增加之间存在相关性。数据表明，至少有一个严重肺栓塞危险因素的患者更有可能出现汉普顿驼峰。此外，在诊断为肺栓塞和胸腔积液的患者中出现此征象会显著增加住院死亡风险。：本研究强调了汉普顿驼峰作为肺栓塞患者中一种罕见但具有临床相关性的影像学表现的重要性。鉴于关于该主题的研究数量有限，我们的发现为汉普顿驼峰在肺栓塞背景下的作用提供了有价值的见解。
