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外源性蛋白质作为肾病范围蛋白尿的病因。

Exogenous protein as the cause of nephrotic-range proteinuria.

作者信息

Mitas J A

出版信息

Am J Med. 1985 Jul;79(1):115-8. doi: 10.1016/0002-9343(85)90554-6.

DOI:10.1016/0002-9343(85)90554-6
PMID:4014295
Abstract

Hematuria and proteinuria developed in a young woman with waxing and waning symptoms suggestive of systemic lupus erythematosus. Quantitatively, the proteinuria was in the nephrotic range, but other manifestations of the nephrotic syndrome were absent. Serologic evaluation demonstrated normal results. The hematuria was subsequently found to be self-induced and related to foreign objects in the bladder. Urine protein electrophoresis confirmed severe proteinuria with a spike in the gamma region. Immunoelectrophoresis demonstrated that the proteinuria was not of human origin. Subsequent urinary protein values were normal. This case exhibits features compatible with Münchausen's syndrome and shows that severe proteinuria may be factitious.

摘要

一名年轻女性出现血尿和蛋白尿,症状反复,提示系统性红斑狼疮。定量分析显示蛋白尿处于肾病范围,但无肾病综合征的其他表现。血清学检查结果正常。随后发现血尿是自我诱导的,与膀胱内异物有关。尿蛋白电泳证实存在严重蛋白尿,γ区有一个峰。免疫电泳显示蛋白尿并非来源于人体。随后的尿蛋白值恢复正常。该病例表现出与孟乔森综合征相符的特征,表明严重蛋白尿可能是人为造成的。

相似文献

1
Exogenous protein as the cause of nephrotic-range proteinuria.外源性蛋白质作为肾病范围蛋白尿的病因。
Am J Med. 1985 Jul;79(1):115-8. doi: 10.1016/0002-9343(85)90554-6.
2
Factitious proteinuria in a young girl.一名年轻女孩的假性蛋白尿
Clin Nephrol. 1990 Jun;33(6):299-302.
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Unusual case of Munchausen's syndrome: factitious vesical lithiasis.孟乔森综合征的罕见病例:人为性膀胱结石
Acta Urol Belg. 1998 Dec;66(4):33-5.
4
Factitious proteinuria - the most dominant feature in a young female patient with Munchausen syndrome.假性蛋白尿——患有孟乔森综合征的年轻女性患者最主要的特征。
Clin Nephrol. 2013 Feb;79(2):166-70.
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Nephrotic range proteinuria and resistant hypertension--is it the egg that came first?
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Diagnosis and management of nephrotic syndrome.肾病综合征的诊断与管理
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Quiz page May 2009: Lymphaticourinary fistula causing chyluria and nephrotic-range proteinuria.2009年5月测验页面:淋巴管-泌尿道瘘导致乳糜尿和肾病范围蛋白尿。
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[Proteinuria and nephrotic syndrome in the child and the adult. Diagnostic orientation].[儿童及成人的蛋白尿与肾病综合征。诊断指南]
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Asymptomatic hematuria and proteinuria in children: causes and appropriate diagnostic studies.
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[Hematuria due to foreign bodies in a woman-patient with the Munchhausen syndrome].[患有孟乔森综合征的女性患者因异物导致的血尿]
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引用本文的文献

1
Renal and urologic manifestations of pediatric condition falsification/Munchausen by proxy.
Pediatr Nephrol. 2007 Jun;22(6):849-56. doi: 10.1007/s00467-007-0431-4. Epub 2007 Feb 14.
2
Munchausen syndrome by proxy with massive proteinuria and gastrointestinal hemorrhage.代理型孟乔森综合征伴大量蛋白尿和胃肠道出血。
Pediatr Nephrol. 2004 Jul;19(7):798-800. doi: 10.1007/s00467-004-1461-9. Epub 2004 Apr 15.