Yu Aiying, Sun Lingli, Chen Lian, Wang Dan, Li Zhiyi, Wang Yuan, Wang Zhenjiang, Lin Sen
Key Laboratory of Urban Agriculture in South China, Sericultural and Agri-Food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Tea Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Front Vet Sci. 2025 Mar 12;12:1565501. doi: 10.3389/fvets.2025.1565501. eCollection 2025.
Proanthocyanidins (PACs) are natural polyphenolic compounds widely distributed in various plants, which are mixtures of oligomers and polymers formed by the polymerization of different numbers of catechins and epicatechins. PACs exhibit a range of biological activities, including antioxidant, anti-inflammatory, anti-cancer, anti-atherosclerotic, hypoglycemic, and antihypertensive effects, as well as the ability to regulate intestinal flora and promote fat metabolism. These properties render PACs highly promising for applications in the food, pharmaceutical, and cosmetic industries, garnering substantial interest from researchers globally. Additionally, PACs demonstrate significant nutritional benefits in animal husbandry. Dietary PACs can enhance animal growth, mitigate oxidative stress, decrease feeding expenses, and offer an environmentally friendly, antibiotic-free alternative. Therefore, PACs have great application potential in the field of pig production. This article reviews the basic properties, biological functions, and research status and application in pig production of PACs, aiming to provide theoretical guidance for the development of substitute antibiotic feed additives.
原花青素(PACs)是广泛分布于各种植物中的天然多酚化合物,它们是由不同数量的儿茶素和表儿茶素聚合而成的低聚物和聚合物的混合物。PACs具有一系列生物活性,包括抗氧化、抗炎、抗癌、抗动脉粥样硬化、降血糖和降血压作用,以及调节肠道菌群和促进脂肪代谢的能力。这些特性使PACs在食品、制药和化妆品行业具有很高的应用前景,引起了全球研究人员的极大兴趣。此外,PACs在畜牧业中也显示出显著的营养益处。日粮中的PACs可以促进动物生长、减轻氧化应激、降低饲养成本,并提供一种环保、无抗生素的替代品。因此,PACs在生猪生产领域具有巨大的应用潜力。本文综述了PACs的基本特性、生物学功能以及在生猪生产中的研究现状和应用,旨在为替代抗生素饲料添加剂的开发提供理论指导。