尿液中医院内分离出的阿萨希毛孢子菌的临床意义：一项回顾性队列研究。
Clinical significance of nosocomial Trichosporon asahii in urine: A retrospective cohort study.
作者信息
Lopez Luis Bruno Ali, León-Palacios Karla Alhelí, Acosta-Ruiz Araceli, Gonzalez-Cardel Ana Maria, Rodriguez-Zuñiga Graciela
机构信息
Department of Infectious Diseases, Centro Medico Nacional, "20 de Noviembre", Instituto de Seguridad Social al Servicio de los Trabajadores del Estado, Mexico City, Mexico.
Department of Infectious Diseases, Centro Medico Nacional, "20 de Noviembre", Instituto de Seguridad Social al Servicio de los Trabajadores del Estado, Mexico City, Mexico.
出版信息
Infect Dis Now. 2025 Aug;55(5):105059. doi: 10.1016/j.idnow.2025.105059. Epub 2025 Mar 25.
OBJECTIVES
To describe the clinical characteristics and outcomes of patients with urine cultures positive for Trichosporon sp with nosocomial acquisition.
METHODS
Retrospective cohort study between 2019 and 2023 that included all patients with urinary isolates of Trichosporon sp; their clinical data and outcomes were drawn from medical records.
RESULTS
Twenty-six patients had urinary Trichosporon asahii. Length of hospital stay before urinary culture with T. asahii averaged 25 days. Seventy percent stayed in the intensive care unit. All patients had an additional bacterial infection and were receiving antibiotic therapy. During the first 30 days, only 57 % were alive. There were no factors significantly associated with mortality.
CONCLUSIONS
The isolation of T. asahii in urine cultures of patients with extended hospital stay does not suggest invasive disease. T. asahii in urine may be a marker of critically ill patients with a high risk of mortality.
目的
描述医院获得性毛孢子菌属尿液培养阳性患者的临床特征及结局。
方法
2019年至2023年的回顾性队列研究，纳入所有尿液分离出毛孢子菌属的患者；其临床资料及结局取自病历。
结果
26例患者尿液中分离出阿萨希毛孢子菌。尿液培养出阿萨希毛孢子菌前的平均住院时长为25天。70%的患者入住重症监护病房。所有患者均合并其他细菌感染且正在接受抗生素治疗。在最初30天内，仅有57%的患者存活。没有与死亡率显著相关的因素。
结论
长期住院患者尿液培养中分离出阿萨希毛孢子菌并不提示侵袭性疾病。尿液中的阿萨希毛孢子菌可能是死亡率高的危重症患者的一个标志物。
Zotero 插件