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Single-Cell Revelations in Tricuspid Valve Remodeling: A New Chapter in Functional Tricuspid Regurgitation.

作者信息

Jiang Xinghang, Huang Jijun

机构信息

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, USA.

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, USA.

出版信息

JACC Asia. 2025 Mar;5(3 Pt 2):499-502. doi: 10.1016/j.jacasi.2025.02.009.

DOI:10.1016/j.jacasi.2025.02.009
PMID:40148024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12042978/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5c3/12042978/6dd357c5b571/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5c3/12042978/1f00ea975a5a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5c3/12042978/6dd357c5b571/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5c3/12042978/1f00ea975a5a/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a5c3/12042978/6dd357c5b571/gr1.jpg

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本文引用的文献

1
Single-Cell Transcriptomics Identified Fibrosis-Activated Valve Interstitial Cells Involved in Functional Tricuspid Regurgitation.单细胞转录组学鉴定出参与功能性三尖瓣反流的纤维化激活瓣膜间质细胞。
JACC Asia. 2025 Mar;5(3 Pt 2):478-495. doi: 10.1016/j.jacasi.2025.01.013.
2
APOE-NOTCH axis governs elastogenesis during human cardiac valve remodeling.载脂蛋白 E-NOTCH 轴调控人心脏瓣膜重塑过程中的弹性生成。
Nat Cardiovasc Res. 2024 Aug;3(8):933-950. doi: 10.1038/s44161-024-00510-3. Epub 2024 Jul 24.
3
Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with other cardiovascular diseases.
高血压中心血管和血管周围肌成纤维细胞、基质成纤维细胞和免疫成纤维细胞；与其他心血管疾病的异同。
Cardiovasc Res. 2024 May 7;120(6):567-580. doi: 10.1093/cvr/cvae044.
4
Cellular Landscapes of Nondiseased Human Cardiac Valves From End-Stage Heart Failure-Explanted Heart.末期心力衰竭-心脏移植患者非病变人类心脏瓣膜的细胞图谱。
Arterioscler Thromb Vasc Biol. 2022 Dec;42(12):1429-1446. doi: 10.1161/ATVBAHA.122.318314. Epub 2022 Oct 6.
5
Single-cell RNA sequencing reveals the diversity and biology of valve cells in cardiac valve disease.单细胞 RNA 测序揭示了心脏瓣膜疾病中瓣膜细胞的多样性和生物学特征。
J Cardiol. 2023 Jan;81(1):49-56. doi: 10.1016/j.jjcc.2022.03.012. Epub 2022 Apr 9.
6
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2020美国心脏病学会/美国心脏协会瓣膜性心脏病患者管理指南：美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
J Am Coll Cardiol. 2021 Feb 2;77(4):e25-e197. doi: 10.1016/j.jacc.2020.11.018. Epub 2020 Dec 17.
7
The tricuspid valve also maladapts as shown in sheep with biventricular heart failure.三尖瓣也会出现不适应，如在双心室心力衰竭的绵羊中所示。
Elife. 2020 Dec 15;9:e63855. doi: 10.7554/eLife.63855.
8
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Arterioscler Thromb Vasc Biol. 2020 Dec;40(12):2910-2921. doi: 10.1161/ATVBAHA.120.314789. Epub 2020 Oct 22.
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Maturation of heart valve cell populations during postnatal remodeling.心脏瓣膜细胞群体在出生后重塑过程中的成熟。
Development. 2019 Mar 12;146(12):dev173047. doi: 10.1242/dev.173047.
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Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart.单细胞转录组分析描绘了人类心脏的发育轨迹。
Cell Rep. 2019 Feb 12;26(7):1934-1950.e5. doi: 10.1016/j.celrep.2019.01.079.