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喉咽反流病管理中的决策:抗酸剂、藻酸盐及饮食的作用

Decision Making in the Managment of Laryngopharyngeal Reflux Disease: Antacids, Alginates, and the Role of Diet.

作者信息

Daniero James J

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Virginia, PO Box 800713, Charlottesville, VA 22908-0713, USA.

出版信息

Otolaryngol Clin North Am. 2025 Jun;58(3):519-527. doi: 10.1016/j.otc.2025.01.007. Epub 2025 Mar 26.

DOI:10.1016/j.otc.2025.01.007
PMID:40148168
Abstract

Laryngopharyngeal reflux and gastroesophageal reflux disease, have significant impact on quality of life and health care costs. Antacids, alginates, and diet modifications are non-prescription interventions that can help to manage these conditions with limited risk of side-effects. Alginates have emerged as a unique mechanism of treatment to block reflux episodes. When combined with dietary interventions that target reflux triggers, alginates demonstrate enhanced efficacy in managing symptoms and promoting mucosal healing. This article explores the role of antacids, alginates, and diet in reflux management, focusing on their combined impact on symptom relief, patient outcomes, and long-term management strategies.

摘要

喉咽反流和胃食管反流病对生活质量和医疗费用有重大影响。抗酸剂、藻酸盐和饮食调整是非处方干预措施,有助于管理这些病症,且副作用风险有限。藻酸盐已成为一种独特的治疗机制,可阻断反流发作。当与针对反流触发因素的饮食干预相结合时,藻酸盐在管理症状和促进黏膜愈合方面显示出更高的疗效。本文探讨抗酸剂、藻酸盐和饮食在反流管理中的作用,重点关注它们对症状缓解、患者预后和长期管理策略的综合影响。

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