Bussell Mark, Sahba Kyan, Jahromi Hailey, Rashidian Mitra, Hankins Jamie
Neuropathic Therapy Center, Loma Linda University Health, Loma Linda, CA 92354, USA.
Department of Allied Health Studies, Loma Linda University, Loma Linda, CA 92354, USA.
Biomedicines. 2025 Mar 11;13(3):688. doi: 10.3390/biomedicines13030688.
: To evaluate the effectiveness of our dual approach in treating neural ischemia. : Researchers were able to retrospectively audit patient data collected from January 2022-September 2024. Patients were included if they received intraneural facilitation (INF), participated in neurovascular index (NVI)-guided food elimination, and completed pre and post pain-quality assessment scale (PQAS) forms in its entirety. : Eighteen of the twenty PQAS descriptive pain variables were significantly different pre- vs. post treatment: intense ( = 0.000), sharp ( = 0.002), hot ( = 0.020), dull ( = 0.022), cold ( = 0.005), sensitive ( = 0.000), shooting ( = 0.000), numb ( = 0.000), electrical ( = 0.000), tingling ( = 0.000), cramping ( = 0.000), radiating ( = 0.000), throbbing ( = 0.000), aching ( = 0.000), heavy ( = 0.000), unpleasant ( = 0.000), deep pain ( = 0.000), and intense surface pain ( = 0.000). Itchy ( = 0.058) and tender ( = 0.062) were not found to be significant. There was also significance in pain decrease in the three mean domains: paroxysmal ( = 0.000), superficial ( = 0.000), and deep ( = 0.000). : This study suggests that blending a mechanical intervention (INF) with a lifestyle modification (NVI-guided food elimination) is effective in improving PQAS scores in patients with peripheral neuropathy, indicating a possible reversal of neural ischemia and maintenance of capillary patency.
评估我们的双重方法治疗神经缺血的有效性。研究人员能够回顾性审查2022年1月至2024年9月收集的患者数据。如果患者接受了神经内促进(INF)、参与了神经血管指数(NVI)指导的食物排除,并完整填写了疼痛质量评估量表(PQAS)的前后表格,则纳入研究。在20个PQAS描述性疼痛变量中,有18个在治疗前后有显著差异:剧烈疼痛(P = 0.000)、刺痛(P = 0.002)、热痛(P = 0.020)、钝痛(P = 0.022)、冷痛(P = 0.005)、敏感(P = 0.000)、放射痛(P = 0.000)、麻木(P = 0.000)、电击样痛(P = 0.000)、刺痛感(P = 0.000)、痉挛痛(P = 0.000)、放射痛(P = 0.000)、搏动性痛(P = 0.000)、酸痛(P = 0.000)、沉重感(P = 0.000)、不适感(P = 0.000)、深部疼痛(P = 0.000)和强烈的体表疼痛(P = 0.000)。瘙痒(P = 0.058)和压痛(P = 0.062)无显著差异。三个平均疼痛领域的疼痛减轻也有显著性:阵发性(P = 0.000)、浅表性(P = 0.000)和深部(P = 0.000)。本研究表明,将机械干预(INF)与生活方式改变(NVI指导的食物排除)相结合可有效提高周围神经病变患者的PQAS评分,表明神经缺血可能得到逆转,毛细血管通畅得以维持。