Park Sanghyuk, Squires James
Department of Animal Biosciences, University of Guelph, Guelph, ON N1G 2W1, Canada.
Animals (Basel). 2025 Mar 7;15(6):765. doi: 10.3390/ani15060765.
The utility of four mineral adsorbents as potential feed additives to bind the boar taint compounds, androstenone and skatole, was assessed with an in vitro system. The adsorbents were bentonite (BNT), diatomaceous earth (DE), spent filter aid (SFA) and hydrated sodium-calcium aluminosilicate (HSCAS), with activated charcoal (AC) as a positive control. The binding capacity (B) and binding affinity (K) of androstenone (AND), estrone (E1), estrone sulfate (E1S), and skatole were estimated using the modified Michaelis-Menten kinetics. The Langmuir and Freundlich isotherm models were also used to assess the adsorption behaviour. The B values with AND were 77.7 ± 1.12%, 71.9 ± 1.93%, 55.0 ± 7.85%, and 69.5 ± 1.39% for BNT, DE, SFA, and HSCAS, respectively, with no differences in the binding affinity K ( > 0.05). All the mineral adsorbents had very low binding with E1S. SFA bound skatole with a B of 89.9 ± 1.09%, while the B values for skatole binding by BNT, DE and HCAS were approximately 15%. Most adsorbent-adsorbate complexes fit best with the Freundlich isotherm model. We conclude that all four mineral adsorbents bound androstenone, but not E1S, and only SFA effectively bound skatole. This suggests that SFA may act as a selective dietary binding agent to control boar taint, but further research using animal models is needed to explore the utility and selectivity of these adsorbents as feed additives to control boar taint.
利用体外系统评估了四种矿物吸附剂作为潜在饲料添加剂结合公猪异味化合物雄烯酮和粪臭素的效用。吸附剂为膨润土（BNT）、硅藻土（DE）、废助滤剂（SFA）和水合钠钙铝硅酸盐（HSCAS），以活性炭（AC）作为阳性对照。使用修正的米氏动力学估算雄烯酮（AND）、雌酮（E1）、硫酸雌酮（E1S）和粪臭素的结合容量（B）和结合亲和力（K）。还使用朗缪尔和弗伦德利希等温线模型评估吸附行为。BNT、DE、SFA和HSCAS对AND的B值分别为77.7±1.12%、71.9±1.93%、55.0±7.85%和69.5±1.39%，结合亲和力K无差异（>0.05）。所有矿物吸附剂与E1S的结合都非常低。SFA结合粪臭素的B值为89.9±1.09%，而BNT、DE和HCAS结合粪臭素的B值约为15%。大多数吸附剂-吸附质复合物最符合弗伦德利希等温线模型。我们得出结论，所有四种矿物吸附剂都能结合雄烯酮，但不能结合E1S，只有SFA能有效结合粪臭素。这表明SFA可能作为一种选择性日粮结合剂来控制公猪异味，但需要使用动物模型进行进一步研究，以探索这些吸附剂作为饲料添加剂控制公猪异味的效用和选择性。
