Horovitz Y, Tal I, Keynan A
Arch Dis Child. 1985 Jun;60(6):579-81. doi: 10.1136/adc.60.6.579.
Thirty four infants were studied; 21 with acute gastroenteritis, dehydration, and metabolic acidosis and 13 who served as controls. All infants with metabolic acidosis and without neurological signs had a normal to near normal cerebrospinal fluid acid base balance, but five with metabolic acidosis and severe neurological signs had cerebrospinal fluid acid base disequilibrium. Acute metabolic acidosis in infants may lead to cerebrospinal fluid acid base imbalance causing cerebral dysfunction.
对34名婴儿进行了研究;其中21名患有急性肠胃炎、脱水和代谢性酸中毒,13名作为对照。所有患有代谢性酸中毒且无神经体征的婴儿脑脊液酸碱平衡正常或接近正常,但5名患有代谢性酸中毒且有严重神经体征的婴儿脑脊液酸碱失衡。婴儿急性代谢性酸中毒可能导致脑脊液酸碱失衡,进而引起脑功能障碍。