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糖尿病性夏科氏脊柱表现为马尾综合征:一种不寻常的表现。

Diabetic Charcot spine as cauda equina syndrome: an unusual presentation.

作者信息

Race M C, Keppler J P, Grant A E

出版信息

Arch Phys Med Rehabil. 1985 Jul;66(7):463-5.

PMID:4015360
Abstract

Some 6% to 21% of Charcot joints occur in the spine. The underlying disease is usually tabes dorsalis, but diabetes mellitus is another etiology. Degeneration of spinal elements is accelerated and lumbar spinal stenosis with weakness may occur, as has been reported in tabetic arthropathy. The case presented is unusual in two respects: first, the Charcot spine was secondary to diabetic complications, which resulted in a compressive cauda equina syndrome; second, the patient presented with progressive paraparesis and bowel and bladder dysfunction but physical examination by several examiners revealed no clinically evident sensory abnormality. The patient had vague and inconsistent sensory complaints for several years preceding definitive workup, but the overall picture of his disease process only could be made following multiple laboratory, electrodiagnostic, microbiologic, and radiologic testing. The patient presented with subacute paraparesis, providing a wide differential diagnosis ranging from Guillain-Barré syndrome to spinal neoplasm. The physical, radiologic, laboratory, electrophysiologic, histologic/pathologic findings, treatment, and recovery status are included in this report.

摘要

约6%至21%的夏科关节发生在脊柱。潜在疾病通常是脊髓痨,但糖尿病也是另一种病因。脊柱结构的退变会加速,可能会出现伴有肌无力的腰椎管狭窄,这在脊髓痨性关节病中已有报道。本病例在两个方面不寻常:第一,夏科脊柱继发于糖尿病并发症,导致马尾神经受压综合征;第二,患者表现为进行性双下肢轻瘫以及肠道和膀胱功能障碍,但多位检查者的体格检查均未发现明显的临床感觉异常。在进行明确检查前的数年里,患者有模糊且不一致的感觉主诉,但只有在进行多次实验室、电诊断、微生物学和放射学检查后,才能全面了解其疾病过程。患者表现为亚急性双下肢轻瘫,鉴别诊断范围广泛,从格林-巴利综合征到脊柱肿瘤。本报告包括体格检查、放射学、实验室、电生理、组织学/病理学检查结果、治疗及恢复情况。

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