Mustafa Asem T, Cahill Kenneth V, Hofer Llwyatt K, Foster Jill A
Yarmouk University Faculty of Medicine, Irbid, Jordan.
Department of Ophthalmology, Nationwide Children's Hospital, Columbus, Ohio, U.S.A.
Ophthalmic Plast Reconstr Surg. 2025;41(5):e165-e167. doi: 10.1097/IOP.0000000000002937. Epub 2025 Mar 28.
A male infant born at full term presented with bilateral upper eyelid colobomas, absent upper puncta, and fusion of the eyelids to the globes. He was admitted for management of bilateral exposure keratopathy and a central corneal ulcer in the right eye. Further examination revealed multiple congenital abnormalities, such as penile torsion, unusual hair growth pattern on the forehead, bifid nasal tip, and hypertelorism. Genetic testing confirmed a diagnosis of Manitoba oculo-tricho-anal syndrome. Because conservative management of the ocular surface was insufficient, bilateral upper eyelid reconstruction surgery was performed 5 days after birth using a vertical temporal advancement flap. At 6-month follow-up, there was excellent eyelid movement and closure with no corneal exposure. This case report describes the clinical findings of a rare bilateral upper eyelid defect and shares an innovative reconstructive technique that readers could mimic if presented with similar congenital upper eyelid defects.
一名足月出生的男婴出现双侧上睑裂缺、上泪小点缺如以及眼睑与眼球融合。他因双侧暴露性角膜病变和右眼中央角膜溃疡入院治疗。进一步检查发现多处先天性异常，如阴茎扭转、前额毛发异常生长模式、鼻尖分叉和眼距过宽。基因检测确诊为曼尼托巴眼-毛-肛门综合征。由于眼表的保守治疗效果不佳，出生后5天采用颞部垂直推进皮瓣进行了双侧上睑重建手术。在6个月的随访中，眼睑运动和闭合良好，无角膜暴露。本病例报告描述了一种罕见的双侧上睑缺损的临床发现，并分享了一种创新的重建技术，读者在遇到类似的先天性上睑缺损时可以模仿。
