Huang Binwei, Zheng Chaoxin, Chen Siyani, Liao Xulong, Chen Haoyu
Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, Guangdong, China.
Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, Shantou, Guangdong, China
BMJ Open Ophthalmol. 2025 Mar 28;10(1):e001965. doi: 10.1136/bmjophth-2024-001965.
To quantitatively investigate the retinal size and shape distortion in different ultra-widefield (UWF) imaging systems.
We imaged the posterior segments of model eyes using Daytona, Mirante, CLARUS 500, VG2001, BMizar and TRC-NW8. We measured the scale bars of each grid and the compactness of each ring to quantify the size and shape distortion. The relationship between the relative size with eccentricity and axial length was analysed. The size and shape distortion were compared among different UWF systems.
The size is positively associated with eccentricity (β=0.202-0.482; p<0.001) and negatively associated with axial length (β=-0.787 to -0.890; p<0.001) in all UWF systems. There is a significant difference in slopes across devices. The size distortion of Mirante is lower than the other UWF systems (p=0.0083-0.0472) except for TRC-NW8. Multivariate linear regression analysis found the adjusted R=0.809-0.948, which was improved to more than 0.960 with a quadratic polynomial equation. Only Daytona showed shape distortion, and the compactness of Daytona is smaller than the others (p<0.0001).
Quantitative measurements identified different relationships between size distortion with axial length and eccentricity in different UWF systems, which can serve as a reference for correcting size distortion. Shape distortion only occurs in Daytona.
定量研究不同超广角（UWF）成像系统中视网膜的大小和形状畸变。
我们使用Daytona、Mirante、CLARUS 500、VG2001、BMizar和TRC-NW8对模型眼的后段进行成像。我们测量了每个网格的比例尺和每个环的紧凑度，以量化大小和形状畸变。分析了相对大小与偏心度和眼轴长度之间的关系。比较了不同UWF系统之间的大小和形状畸变。
在所有UWF系统中，大小与偏心度呈正相关（β=0.202 - 0.482；p<0.001），与眼轴长度呈负相关（β=-0.787至-0.890；p<0.001）。不同设备的斜率存在显著差异。除TRC-NW8外，Mirante的大小畸变低于其他UWF系统（p=0.0083 - 0.0472）。多元线性回归分析发现调整后的R=0.809 - 0.948，使用二次多项式方程可将其提高到0.960以上。仅Daytona显示出形状畸变，且Daytona的紧凑度小于其他系统（p<0.0001）。
定量测量确定了不同UWF系统中大小畸变与眼轴长度和偏心度之间的不同关系，可为校正大小畸变提供参考。形状畸变仅发生在Daytona中。
