嗜酸性肉芽肿性多血管炎累及眼部缺血：病例报告
Ischemic Ocular Involvement in Eosinophilic Granulomatosis with Polyangiitis: A Case Report.
作者信息
Laburthe Sébastien, Loupret Thibaud, Foré Romain, Ly Kim-Heang, Parreau Simon
机构信息
Internal Medicine Department, Dupuytren Hospital, Limoges, France.
Rheumatology Department, Dupuytren Hospital, Limoges, France.
出版信息
Ocul Immunol Inflamm. 2025 Aug;33(6):1070-1072. doi: 10.1080/09273948.2025.2486361. Epub 2025 Mar 28.
PURPOSE
To report an uncommon, ocular ischemic involvement in a patient diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA).
METHODS
Case report.
RESULTS
A 77-year-old male exhibited headaches, scotomas and decreased visual acuity. The temporal artery biopsy revealed necrotizing vasculitis with eosinophilic infiltration. The patient responded to corticosteroid therapy, and no relapses were observed after 24 months of follow-up.
CONCLUSIONS
This case highlights the importance of differentiating EGPA from other ischemic ocular conditions like giant cell arteritis. Temporal artery biopsy remains an essential diagnostic tool in these complex cases, and further guidelines are needed to manage ischemic manifestations in EGPA patients.
目的
报告1例诊断为嗜酸性肉芽肿性多血管炎（EGPA）患者罕见的眼部缺血受累情况。
方法
病例报告。
结果
一名77岁男性出现头痛、暗点和视力下降。颞动脉活检显示坏死性血管炎伴嗜酸性粒细胞浸润。患者对皮质类固醇治疗有反应，随访24个月后未观察到复发。
结论
该病例强调了将EGPA与其他缺血性眼病如巨细胞动脉炎相鉴别的重要性。颞动脉活检仍是这些复杂病例的重要诊断工具，需要进一步的指南来管理EGPA患者的缺血表现。
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