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80岁以上患者髋部骨折术后并发症及院内死亡率的危险因素:一项回顾性研究。

Risk factors of postoperative complications and in-hospital mortality after hip fracture among patients older than 80 years old: a retrospective study.

作者信息

Zhang Huawen, Ma Lulu, Yu Xuerong

机构信息

Department of anesthesiology, Peking Union Medical College Hospital, Beijing, 100730, China.

出版信息

BMC Surg. 2025 Mar 28;25(1):122. doi: 10.1186/s12893-025-02862-4.

Abstract

INDUCTION

The mortality and morbidity in hip fracture is a big healthcare burden. How to identify risk patients preoperatively is important. The aim of study was to evaluate the risk factors of postoperative complications and mortality in patients older than 80 years old after hip fracture surgery.

METHODS

Patients older than 80 years old with the diagnosis of hip fracture who had surgical treatment from February 2013 to June 2021 at a single center in China were included for analysis. The primary outcome were postoperative complications and in-hospital mortality. Binary logistic regression was used to confirm the relationship between preoperative factors and postoperative complications/mortality.

RESULTS

498 patients were included for analysis. 176 patients developed 265 episodes of complications and the incidence of postoperative complication was 35.3%. Postoperative pulmonary infection was the most common complication, followed by cardiovascular complications and postoperative delirium. And there were 10 postoperative in-hospital deaths (2.0%). Preoperative Charlson comorbidity index(CCI) was associated with postoperative complications (OR = 1.243, 95%CI 1.020-1.516, P = 0.031) and mortality (OR = 2.303, 95%CI 1.351-3.925, P = 0.002). However, American society of Anesthesiologists (ASA) score was not an independent risk factor for postoperative complication and mortality.

CONCLUSION

CCI was the risk factor of poor postoperative outcome for patients older than 80 years old after hip fracture surgery. And CCI can be used as the potential tool of risk stratification for this group of patients.

TRIAL REGISTRATION

This study had been registered in www.chictr.org.cn and the registration ID was ChiCTR2400085291 on June 4th 2024.

摘要

引言

髋部骨折的死亡率和发病率是一个巨大的医疗负担。术前如何识别高危患者很重要。本研究的目的是评估80岁以上髋部骨折手术后患者术后并发症和死亡的危险因素。

方法

纳入2013年2月至2021年6月在中国某单一中心接受手术治疗的80岁以上髋部骨折诊断患者进行分析。主要结局是术后并发症和院内死亡率。采用二元逻辑回归确定术前因素与术后并发症/死亡率之间的关系。

结果

498例患者纳入分析。176例患者发生265次并发症,术后并发症发生率为35.3%。术后肺部感染是最常见的并发症,其次是心血管并发症和术后谵妄。术后有10例院内死亡(2.0%)。术前查尔森合并症指数(CCI)与术后并发症(OR = 1.243,95%CI 1.020 - 1.516,P = 0.031)和死亡率(OR = 2.303,95%CI 1.351 - 3.925,P = 0.002)相关。然而,美国麻醉医师协会(ASA)评分不是术后并发症和死亡率的独立危险因素。

结论

CCI是80岁以上髋部骨折手术后患者术后不良结局的危险因素。并且CCI可作为该组患者风险分层的潜在工具。

试验注册

本研究已在www.chictr.org.cn注册,注册ID为2024年6月4日的ChiCTR2400085291。

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Current surgical status of hip fracture among elderly in China.中国老年人髋部骨折的当前手术状况。
Injury. 2024 Feb;55(2):111083. doi: 10.1016/j.injury.2023.111083. Epub 2023 Oct 6.
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Postoperative delirium in geriatric patients with hip fractures.老年髋部骨折患者术后谵妄
Front Aging Neurosci. 2022 Dec 22;14:1068278. doi: 10.3389/fnagi.2022.1068278. eCollection 2022.

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