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踝关节骨折手术后的术后感染:当前概念综述

Post-operative infection following ankle fracture surgery: a current concepts review.

作者信息

Tausendfreund Jasper, Halm Jens, Tanis Erik, Swords Michael, Schepers Tim

机构信息

Trauma Unit, Noordwest Hospital Group, Wilhelminalaan 12, 1815 JD, Alkmaar, The Netherlands.

Trauma Unit, Amsterdam University Medical Center, Amsterdam Movement Sciences, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

出版信息

Eur J Trauma Emerg Surg. 2025 Mar 29;51(1):157. doi: 10.1007/s00068-025-02837-3.

Abstract

PURPOSE

The most common early complication of operative treatment of ankle fractures is a surgical site infection (SSI) with an incidence rate varying between 1.5 and 16%, depending on various risk factors. A SSI has multiple disadvantages, including worse outcome and a socio-economic burden. The aim of this review is to provide an updated overview of the current concepts pertinent to SSI in ankle fractures.

METHODS

A descriptive literature review was performed to provide the overview.

RESULTS

Well known risk factors for SSI are higher age, diabetes, open fractures and fracture dislocation. Diagnostic testing for infection include laboratory results (CRP, white blood cell count, leucocyte count), radiological imaging methods (conventional imaging, CT-scan, MRI-scan, 3-phase bone scan, FDG-PET) and microbiological deep tissue sampling. Treatment options for SSI are varied and include fracture reduction, antibiotic therapy with intravenous and oral treatment, surgical debridement and irrigation, transposition flaps in case of soft tissue defects with implant exposure and arthrodesis in severe infection with septic arthritis. Multiple studies show worse outcome scores in patients who develop a SSI. Prevention is important to reduce the rate of SSI. Surgery within 24 h decreases the risk of complications, compared to surgery performed in a delayed fashion. Appropriate timing and dosing of preoperative antibiotic prophylaxis is necessary.

CONCLUSION

This review described the most frequent risk factors, appropriate diagnostic testing methods, an oversight of treatment options, gives insight in the outcome and mentioned prevention measurements for SSI after ORIF in ankle fractures.

摘要

目的

踝关节骨折手术治疗最常见的早期并发症是手术部位感染(SSI),其发生率在1.5%至16%之间,具体取决于多种风险因素。手术部位感染有诸多不利之处,包括预后较差以及社会经济负担。本综述的目的是提供有关踝关节骨折手术部位感染的当前概念的最新概述。

方法

进行描述性文献综述以提供该概述。

结果

已知手术部位感染的风险因素包括年龄较大、糖尿病、开放性骨折和骨折脱位。感染的诊断检测包括实验室检查结果(CRP、白细胞计数、白细胞总数)、放射影像学方法(传统影像学、CT扫描、MRI扫描、三相骨扫描、FDG-PET)以及微生物学深部组织采样。手术部位感染的治疗选择多种多样,包括骨折复位、静脉和口服抗生素治疗、手术清创和冲洗、软组织缺损伴植入物外露时的转位皮瓣以及严重感染伴化脓性关节炎时的关节融合术。多项研究表明,发生手术部位感染的患者预后评分较差。预防对于降低手术部位感染率很重要。与延迟手术相比,24小时内进行手术可降低并发症风险。术前抗生素预防的时机和剂量必须恰当。

结论

本综述描述了最常见的风险因素、合适的诊断检测方法、治疗选择概述、对预后的见解,并提及了踝关节骨折切开复位内固定术后手术部位感染的预防措施。

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本文引用的文献

1
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Foot Ankle Spec. 2024 Oct 5:19386400241273105. doi: 10.1177/19386400241273105.
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Eur J Trauma Emerg Surg. 2024 Aug;50(4):1701-1707. doi: 10.1007/s00068-024-02497-9. Epub 2024 Apr 9.
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Wound complication risk factors following open reduction and internal fixation of ankle fractures.
Int Wound J. 2024 Apr;21(4):e14581. doi: 10.1111/iwj.14581. Epub 2023 Dec 19.
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Local administration of vancomycin powder in orthopaedic fracture surgery: current practice and trends.
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