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轻度或中度上呼吸道感染儿童通气设备的选择:一项随机对照试验

The selection of ventilation devices in children with mild or moderate upper respiratory tract infections: a randomised controlled trial.

作者信息

Shi Jing, Liu Xiang, Chen Wenjing, Bao Wenjuan

机构信息

Department of Anesthesiology, Hebei Children's Hospital, NO.166 jianhuanan street, Shijiazhuang, Hebei, 050000, China.

出版信息

Trials. 2025 Mar 29;26(1):112. doi: 10.1186/s13063-025-08815-9.

Abstract

PURPOSE

Administering anaesthesia to children with upper respiratory tract infections (URTIs) increases the risk of perioperative respiratory adverse events (PRAEs). Several observational studies have suggested that the supraglottic airway (SGA) technique could be a potential alternative for airway management in children. This randomised controlled trial assesses whether using a SGA instead of an endotracheal tube (ETT) in children with mild or moderate URTIs affects the incidence of PRAEs.

METHODS

A total of 78 paediatric patients with mild or moderate URTIs who received either a SGA or ETT were included. Patients were monitored for adverse events such as cough, laryngospasm, bronchospasm, breath-holding, postoperative stridor or desaturation (< 90%) during the following stages: induction of anaesthesia, tube placement, surgery, tube removal and postanaesthesia care.

RESULTS

Throughout the perioperative period, 56.4% (44/78) of children experienced PRAEs. The incidence was 77.5% (31/40) in those receiving ETT and 34.1% (13/38) in those receiving SGA. The relative risk (RR) of PRAEs in children receiving SGA was 0.417 (95% CI: 0.248-0.701) compared with those receiving ETT (p < 0.001). Specifically, the incidence of minor PRAEs was significantly lower in the SGA group (28.9%, 11/38) compared with the ETT group (67.5%, 27/40) (RR: 0.429, 95% CI: 0.249-0.738, p < 0.001). There were significant differences between the groups in the incidence of perioperative cough (p = 0.043) and desaturation (p = 0.031).

CONCLUSION

Using a SGA reduced the incidence of coughing, bronchospasm and oxygen desaturation, providing an acceptable alternative to ETT in children with mild or moderate URTIs.

摘要

目的

对上呼吸道感染(URTIs)患儿实施麻醉会增加围手术期呼吸不良事件(PRAEs)的风险。多项观察性研究表明,声门上气道(SGA)技术可能是儿童气道管理的一种潜在替代方法。这项随机对照试验评估了在轻度或中度URTIs患儿中使用SGA而非气管内插管(ETT)是否会影响PRAEs的发生率。

方法

总共纳入了78例接受SGA或ETT的轻度或中度URTIs儿科患者。在麻醉诱导、插管、手术、拔管和麻醉后护理等阶段,对患者的咳嗽、喉痉挛、支气管痉挛、屏气、术后喘鸣或血氧饱和度降低(<90%)等不良事件进行监测。

结果

在整个围手术期,56.4%(44/78)的儿童发生了PRAEs。接受ETT的儿童发生率为77.5%(31/40),接受SGA的儿童发生率为34.1%(13/38)。与接受ETT的儿童相比,接受SGA的儿童发生PRAEs的相对风险(RR)为0.417(95%CI:0.248 - 0.701)(p < 0.001)。具体而言,SGA组轻微PRAEs的发生率(28.9%,11/38)显著低于ETT组(67.5%,27/40)(RR:0.429,95%CI:0.249 - 0.738,p < 0.001)。两组在围手术期咳嗽发生率(p = 0.043)和血氧饱和度降低发生率(p = 0.031)方面存在显著差异。

结论

使用SGA可降低咳嗽、支气管痉挛和血氧饱和度降低的发生率,为轻度或中度URTIs患儿提供了一种可接受的ETT替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57e1/11954290/38574dfdd071/13063_2025_8815_Fig1_HTML.jpg

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