Crick J C, Davies D W, Holt P, Curry P V, Sowton E
Br Heart J. 1985 Jul;54(1):80-5. doi: 10.1136/hrt.54.1.80.
Ten patients with Wolff-Parkinson-White syndrome underwent cardiac electrophysiological study extended to include the induction of atrial fibrillation at maximum exercise in the upright position. This was performed using a new temporary bipolar lead with a helical active fixation tip for atrial pacing. The highest rate of atrioventricular conduction via the accessory pathway was greater during exercise than at rest in all 10 patients (mean increase 28%). In three cases the resulting ventricular rate exceeded 300 beats/min, but no patient had severe symptoms or ventricular arrhythmias. The exercise induced enhancement of accessory pathway conduction may significantly but unpredictably affect the risk from spontaneous atrial fibrillation especially in patients with coronary artery disease or in those taking antiarrhythmic drugs. The test procedure was sufficiently simple and well tolerated to be included in our routine electrophysiological investigation.
10例预激综合征患者接受了心脏电生理研究，研究范围扩大至包括在直立位最大运动量时诱发房颤。这是使用一种新型临时双极导联进行的，该导联具有用于心房起搏的螺旋状主动固定尖端。在所有10例患者中，经旁路的房室传导最高速率在运动时高于静息时（平均增加28%）。3例患者由此产生的心室率超过300次/分钟，但无患者出现严重症状或室性心律失常。运动诱发的旁路传导增强可能会显著但不可预测地影响自发性房颤的风险，尤其是在冠心病患者或服用抗心律失常药物的患者中。该测试程序足够简单且耐受性良好，可纳入我们的常规电生理检查。
