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宫颈癌免疫检查点抑制剂(ICI)领域的研究热点与趋势:一项2014年至2024年的文献计量学研究

Research hotspots and trends in the field of immune checkpoint inhibitors (ICIs) for cervical cancer: A bibliometric study from 2014 to 2024.

作者信息

Shen Chaoyan, Zhang Juan, Zhang Guanyu, Luo Hao, Zhang Shuangke, Yuan Quan, Xu Wei, Wang Wei, Miao Lele

机构信息

Department of Ultrasound, Jining NO.1 People's Hospital, Jining, China.

Department of Hematology, Jining NO.1 people' Hospital, Jining, China.

出版信息

Hum Vaccin Immunother. 2025 Dec;21(1):2483031. doi: 10.1080/21645515.2025.2483031. Epub 2025 Mar 31.

DOI:10.1080/21645515.2025.2483031
PMID:40159879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959921/
Abstract

In recent years, immune checkpoint inhibitors (ICIs) have emerged as a novel immunotherapeutic approach, offering renewed hope for enhancing cervical cancer patient prognosis. This study represents the inaugural bibliometric analysis of ICIs in the context of cervical cancer, covering the period from 2014 to 2024. A total of 422 articles were identified through the Web of Science Core Collection database, amassing 10,977 citations, with a consistent annual increase in the number of publications. The leading contributors in terms of countries, institutions, journals, and authors included China, the University of Texas System, , and Bradley J. Monk, respectively. The journal with the highest frequency of citation and co-citation was . The researchers with the highest number of citations and co-citations were Sarina A Piha-Paul and Krishnansu S Tewari respectively. The keyword cluster analysis identified four main research directions. Furthermore, literature co-citation analysis and burst citation analysis revealed three research hotspots and four potential emerging topics within this domain, respectively. This study provides valuable reference and enlightenment for researchers in this field. As research progresses, ICIs are anticipated to offer significant hope and breakthroughs in the treatment of cervical cancer.

摘要

近年来,免疫检查点抑制剂(ICIs)已成为一种新型免疫治疗方法,为改善宫颈癌患者预后带来了新的希望。本研究是对宫颈癌背景下ICIs的首次文献计量分析,涵盖2014年至2024年期间。通过Web of Science核心合集数据库共识别出422篇文章,累积被引次数达10977次,且出版物数量逐年持续增加。在国家、机构、期刊和作者方面的主要贡献者分别为中国、德克萨斯大学系统和布拉德利·J·蒙克。被引频次和共被引频次最高的期刊是 。被引频次和共被引频次最高的研究人员分别是萨琳娜·A·皮哈 - 保罗和克里什南苏·S·特瓦里。关键词聚类分析确定了四个主要研究方向。此外,文献共被引分析和突发被引分析分别揭示了该领域内的三个研究热点和四个潜在新兴主题。本研究为该领域的研究人员提供了有价值的参考和启示。随着研究的进展,预计ICIs将在宫颈癌治疗中带来重大希望和突破。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/a04473ab03c6/KHVI_A_2483031_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/290059f2f789/KHVI_A_2483031_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/8ed599fb09e7/KHVI_A_2483031_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/a04473ab03c6/KHVI_A_2483031_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/290059f2f789/KHVI_A_2483031_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/8ed599fb09e7/KHVI_A_2483031_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d20/11959921/a04473ab03c6/KHVI_A_2483031_F0003_OC.jpg

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本文引用的文献

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A new treatment approach of toripalimab in combination with concurrent platinum-based chemoradiotherapy for locally advanced cervical cancer: A phase II clinical trial.托瑞帕利单抗联合顺铂同步放化疗治疗局部晚期宫颈癌的新治疗方法:一项II期临床试验。
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Efficacy and Safety of Atezolizumab as a PD-L1 Inhibitor in the Treatment of Cervical Cancer: A Systematic Review.阿替利珠单抗作为一种PD-L1抑制剂治疗宫颈癌的疗效和安全性:一项系统评价
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