文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

解析失巢凋亡与癌症的联系：研究趋势和机制的文献计量分析

Unraveling the anoikis-cancer nexus: a bibliometric analysis of research trends and mechanisms.

作者信息

Jiang Junjie, Peng Wei, Sun Nianzhe, Zhao Deze, Cui Weifang, Lai Yuwei, Zhang Chunfang, Duan Chaojun, Zeng Wei

机构信息

Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, People's Republic of China.

Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, Hunan, People's Republic of China.

出版信息

Future Sci OA. 2025 Dec;11(1):2484159. doi: 10.1080/20565623.2025.2484159. Epub 2025 Mar 31.

DOI:10.1080/20565623.2025.2484159
PMID:40160087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11959893/
Abstract

BACKGROUND: Cancer, influenced by genetics and the environment, involves anoikis, a cell death mechanism upon extracellular matrix detachment crucial for metastasis. Understanding this relationship is key for therapy. We analyze cancer and anoikis trends using bibliometrics. METHODS: A search was conducted from Web of Science Core, PubMed, Scopus and non-English databases such as the CNKI (inception- 21 December 2024). Data analysis employed Microsoft Excel, VOSviewer, CiteSpace, R software, and the online platform (https://bibliometric.com/). RESULTS: 2510 publications were retrieved, with a significant increase in the last decade. China led, the University of Texas system was productive, and the Oncogene Journal was popular. Breast, and colorectal cancers were frequently studied. Among them, representative tumor-related mechanisms were identified, commonalities such as (EMT, ECM, autophagy) and respective specific mechanisms were summarized. CONCLUSION: This bibliometric analysis highlights rapid advances in anoikis research in cancer, emphasizing EMT and FAK pathways' translational potential, guiding targeted therapies, and improving cancer treatment outcomes.

摘要

背景：癌症受遗传和环境影响，涉及失巢凋亡，这是一种细胞外基质脱离时的细胞死亡机制，对转移至关重要。理解这种关系是治疗的关键。我们使用文献计量学分析癌症和失巢凋亡的趋势。 方法：从科学网核心库、PubMed、Scopus以及中国知网等非英文数据库（起始时间 - 2024年12月21日）进行检索。数据分析采用微软Excel、VOSviewer、CiteSpace、R软件以及在线平台（https://bibliometric.com/）。 结果：共检索到2510篇出版物，在过去十年中有显著增加。中国排名第一，德克萨斯大学系统产出颇丰，《癌基因杂志》很受欢迎。乳腺癌和结直肠癌是研究较多的癌症。其中，确定了代表性的肿瘤相关机制，总结了诸如（上皮 - 间质转化、细胞外基质、自噬）等共性以及各自的特定机制。 结论：这项文献计量分析突出了癌症失巢凋亡研究的快速进展，强调了上皮 - 间质转化和粘着斑激酶途径的转化潜力，为靶向治疗提供指导并改善癌症治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/ae119779b163/IFSO_A_2484159_F0005_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/9a2e83349c29/IFSO_A_2484159_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/330b1209e419/IFSO_A_2484159_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/c7e49340fd49/IFSO_A_2484159_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/3dcfece65079/IFSO_A_2484159_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/ae119779b163/IFSO_A_2484159_F0005_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/9a2e83349c29/IFSO_A_2484159_F0001_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/330b1209e419/IFSO_A_2484159_F0002_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/c7e49340fd49/IFSO_A_2484159_F0003_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/3dcfece65079/IFSO_A_2484159_F0004_C.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d84f/11959893/ae119779b163/IFSO_A_2484159_F0005_C.jpg

相似文献

[1]
Unraveling the anoikis-cancer nexus: a bibliometric analysis of research trends and mechanisms.

Future Sci OA. 2025-12

[2]
Bibliometric analysis of laryngeal cancer treatment literature (2003-2023).

Heliyon. 2024-12-16

[3]
A bibliometric and visual analysis of cancer-associated fibroblasts.

Front Immunol. 2023

[4]
Global trends in tumor-associated neutrophil research: a bibliometric and visual analysis.

Front Immunol. 2025-3-14

[5]
Research Trends in the Application of Artificial Intelligence in Oncology: A Bibliometric and Network Visualization Study.

Front Biosci (Landmark Ed). 2022-8-31

[6]
Global research trends of artificial intelligence applied in esophageal carcinoma: A bibliometric analysis (2000-2022) CiteSpace and VOSviewer.

Front Oncol. 2022-8-25

[7]
Bibliometric study of immunotherapy for hepatocellular carcinoma.

Front Immunol. 2023

[8]
A bibliometric and knowledge-map analysis of anoikis from 2003 to 2022.

Apoptosis. 2024-4

[9]
Research Trends and Hot Spots of Allopregnanolone Research in the Last 20 Years: A Bibliometric Analysis.

Drug Des Devel Ther. 2023

[10]
Research trends on the relationship between gut microbiota and colorectal cancer: A bibliometric analysis.

Front Cell Infect Microbiol. 2022

本文引用的文献

[1]
Current Status and Future Directions of Artificial Intelligence in Post-Traumatic Stress Disorder: A Literature Measurement Analysis.

Behav Sci (Basel). 2024-12-30

[2]
The roles of KRAS in cancer metabolism, tumor microenvironment and clinical therapy.

Mol Cancer. 2025-1-13

[3]
mRNA-Lipid Nanoparticle-Mediated Restoration of PTPN14 Exhibits Antitumor Effects by Overcoming Anoikis Resistance in Triple-Negative Breast Cancer.

Adv Sci (Weinh). 2024-8

[4]
RNA epigenetics in pulmonary diseases: Insights into methylation modification of lncRNAs in lung cancer.

Biomed Pharmacother. 2024-6

[5]
A bibliometric analysis of the application of the PI3K-AKT-mTOR signaling pathway in cancer.

Naunyn Schmiedebergs Arch Pharmacol. 2024-10

[6]
YAP/TAZ-mediated regulation of laminin 332 is enabled by β4 integrin repression of ZEB1 to promote ferroptosis resistance.

J Biol Chem. 2024-4

[7]
Preliminary guideline for reporting bibliometric reviews of the biomedical literature (BIBLIO): a minimum requirements.

Syst Rev. 2023-12-15

[8]
Knowledge mapping and emerging trends of ferroptosis in ischemia reperfusion injury research: A bibliometric analysis (2013-2022).

Heliyon. 2023-9-21

[9]
Cancer metastasis: Molecular mechanisms and clinical perspectives.

Pharmacol Ther. 2023-10

[10]
Trends in Diet and Cancer Research: A Bibliometric and Visualization Analysis.

Cancers (Basel). 2023-7-25

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索