Chandan Nakul, Ashok Vishnu, Hwang Taesoon, Lim Ven Gee, Lachlan Thomas, Eftekhari Helen, McGregor Gordon, Osman Faizel
Institute for Cardiometabolic Medicine, University Hospitals Coventry & Warwickshire NHS Trust, CV2 2DX Coventry, UK.
Centre for Healthcare & Communities, Coventry University, CV1 5FB Coventry, UK.
Rev Cardiovasc Med. 2025 Mar 21;26(3):27175. doi: 10.31083/RCM27175. eCollection 2025 Mar.
The global prevalence of atrial fibrillation (AF) is growing with a significant increase in AF burden. The pathophysiology of AF is complex and exhibits a strong relationship with modifiable lifestyle AF risk factors, such as physical inactivity, smoking, obesity, and alcohol consumption, as well as co-morbidities, such as hypertension, diabetes mellitus, and cardiovascular disease. Current evidence suggests that cardiac rehabilitation and lifestyle risk factor modification can potentially lower the overall AF burden. Additionally, AF ablation can be an effective treatment for a rhythm control strategy, but reducing AF recurrences post-catheter ablation is paramount. Thus, addressing these modifiable lifestyle risk factors and co-morbidities is critical, as the recent 2024 European Society of Cardiology AF guidance update highlights. A comprehensive approach to treating these risk factors is essential, especially given the rising prevalence of AF. This article provides a state-of-the-art update on the evidence of addressing AF-related risk factors and co-morbidities, particularly in patients undergoing AF ablation.
全球心房颤动（AF）的患病率正在上升，AF负担显著增加。AF的病理生理学很复杂，并且与可改变的生活方式AF风险因素（如身体活动不足、吸烟、肥胖和饮酒）以及合并症（如高血压、糖尿病和心血管疾病）密切相关。目前的证据表明，心脏康复和生活方式风险因素的改变可能会降低总体AF负担。此外，AF消融可以是一种有效的节律控制策略治疗方法，但减少导管消融术后的AF复发至关重要。因此，正如最近2024年欧洲心脏病学会AF指南更新所强调的，解决这些可改变的生活方式风险因素和合并症至关重要。鉴于AF患病率不断上升，采用综合方法治疗这些风险因素至关重要。本文提供了关于解决AF相关风险因素和合并症证据的最新进展，特别是在接受AF消融的患者中。
